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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2024-14-4-394-400</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-1027</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Современные подходы к диагностике и лечению острого панкреатита (клинический случай)</article-title><trans-title-group xml:lang="en"><trans-title>Acute Pancreatitis (A Clinical Case)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7669-0835</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хрипун</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Khripun</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хрипун Алексей Иванович — д.м.н., профессор, кафедра хирургии и эндоскопии</p><p> </p></bio><bio xml:lang="en"><p>Aleksey I. Khripun — Dr. Sci. (Med.), Prof., Department of Surgery and Endoscopy</p><p>Moscow</p><p> </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1919-6504</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алимов</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Alimov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Алимов Александр Николаевич — д.м.н., профессор, кафедра хирургии и эндоскопии</p><p> </p></bio><bio xml:lang="en"><p>Aleksandr N. Alimov — Dr. Sci. (Med.), Prof., Department of Surgery and Endoscopy</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4245-6113</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлов</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlov</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орлов Станислав Юрьевич — к.м.н., доцент, кафедра хирургии и эндоскопии</p><p> </p></bio><bio xml:lang="en"><p>Stanislav Yu. Orlov — Cand. Sci. (Med.), Assoc. Prof.</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-2916-7573</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Челяпина</surname><given-names>Т. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Chelyapina</surname><given-names>T. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Челяпина Татьяна Петровна — аспирант, кафедра хирургии и эндоскопии</p><p> </p></bio><bio xml:lang="en"><p>Tatyana P. Chelyapina — Postgraduate Student, Department of Surgery and Endoscopy</p><p>Moscow</p></bio><email xlink:type="simple">tchelyapina@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский национальный исследовательский медицинский университет им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>29</day><month>12</month><year>2024</year></pub-date><volume>14</volume><issue>4</issue><fpage>394</fpage><lpage>400</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хрипун А.И., Алимов А.Н., Орлов С.Ю., Челяпина Т.П., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Хрипун А.И., Алимов А.Н., Орлов С.Ю., Челяпина Т.П.</copyright-holder><copyright-holder xml:lang="en">Khripun A.I., Alimov A.N., Orlov S.Y., Chelyapina T.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/1027">https://www.surgonco.ru/jour/article/view/1027</self-uri><abstract><sec><title>Введение</title><p>Введение. Диагностика острого панкреатита на сегодняшний день не вызывает затруднений. В то же время в ранние сроки потенциально тяжелое течение заболевания не всегда возможно адекватно прогнозировать с помощью существующих методов диагностики. Запоздалая диагностика панкреонекроза и несвоевременное начало интенсивной терапии способствуют более тяжелому течению заболевания.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Представлен случай повторного холедохолитиаза, явившегося причиной осложненного течения острого билиарного панкреатита у женщины 58 лет. Стандартизированная методика эндоскопической ультрасонографии позволила своевременно выявить признаки развивающегося панкреонекроза и прервать его прогрессирование путем выполнения папиллосфинктеротомии, холедохолитоэкстракции и панкреатического стентирования.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Эндосонографические признаки панкреонекроза доступны для визуализации в начальном периоде острого панкреатита. Такие изменения, как вирсунгэктазия и гипоэхогенные очаги в паренхиме поджелудочной железы, дают основания полагать, что стентирование панкреатического протока будет иметь клиническую эффективность. Выполнение эндоскопических ретроградных вмешательств при остром панкреатите, в частности панкреатическое стентирование, позволяет остановить прогрессирование панкреонекроза и способствуют скорейшему клинико-лабораторному выздоровлению.</p></sec><sec><title>Заключение</title><p>Заключение. Представленный случай демонстрирует высокую информативность и эффективность эндоскопических методов в ранней диагностике и лечении острого билиарного панкреатита.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>ntroduction</title><p>ntroduction. The diagnosis of acute pancreatitis poses no significant difficulties. Nonetheless, accurately predicting the potential severity of the disease during its early stages remains a challenge with existing diagnostic methods. Delayed diagnosis of pancreatic necrosis and the late initiation of intensive therapy contribute to a more severe disease course.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The paper presents a case of recurrent choledocholithiasis as a complicating factor in acute biliary pancreatitis in a 58-year-old woman. A standardized technique of endoscopic ultrasound allowed for the timely identification of signs indicative of developing pancreatic necrosis, enabling the prevention of its progression through papillary sphincterotomy, choledocholithotripsy, and pancreatic stenting.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Endosonographic features of pancreatic necrosis are visualizable in the early stages of acute pancreatitis. Changes such as Wirsung duct dilation and hypoechoic lesions in the pancreatic parenchyma provide grounds for pancreatic duct stenting with an expected clinical efficacy. The performance of endoscopic retrograde interventions in acute pancreatitis, including pancreatic stenting in particular, can halt the progression of pancreatic necrosis and contribute to a more rapid clinical and laboratory recovery.</p></sec><sec><title>Conclusion</title><p>Conclusion. The presented case demonstrates the high informativeness and effectiveness of endoscopic methods in the early diagnosis and treatment of acute biliary pancreatitis.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>билиарный панкреатит</kwd><kwd>панкреонекроз</kwd><kwd>эндоскопическая ретроградная холангиопанкреатография</kwd><kwd>эндосонография</kwd><kwd>панкреатическое стентирование</kwd><kwd>холедохолитиаз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>biliary pancreatitis</kwd><kwd>pancreatic necrosis</kwd><kwd>endoscopic retrograde cholangiopancreatography</kwd><kwd>endosonography</kwd><kwd>pancreatic stenting</kwd><kwd>choledocholithiasis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Iannuzzi J.P., King J.A., Leong J.H., Quan J, Windsor J.W., Tanyingoh D., et al. 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