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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2012-0-2-17-19</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-104</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>МОРФОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА ЛЕТАЛЬНЫХ СЛУЧАЕВ  ПОСЛЕ СПЛЕНЭКТОМИИ В ЭКСПЕРИМЕНТЕ</article-title><trans-title-group xml:lang="en"><trans-title>MORPHOLOGICAL CHARACTERISTIC OF FATAL CASES AFTER SPLENECTOMY UNDER EXPERIMENT</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербулатов</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbulatov</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимербулатов Виль Мамилович - заведующий кафедрой хирургии с курсом эндоскопии и подготовки интернов хирургического профиля, член-кор. РАМН, доктор медицинских наук, профессор</p></bio><bio xml:lang="en"><p>Surgery Chair with  the Сourse of Endoscopy and Training Interns for specialization in surgery  of Institute of Professional Education</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фаязов</surname><given-names>Р. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Fayazov</surname><given-names>R. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Фаязов Радик Радифович - доктор медицинских наук, профессор кафедры хирургии с курсом эндоскопии и подготовки интернов хирургического профиля ИПО БГМУ</p></bio><bio xml:lang="en"><p>Surgery Chair with  the Сourse of Endoscopy and Training Interns for specialization in surgery  of Institute of Professional Education</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чанышев</surname><given-names>Б. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Chanyshev</surname><given-names>B. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чанышев Булат Финатович - аспирант кафедры  хирургии с курсом эндоскопии и подготовки интернов хирургического профиля ИПО БГМУ</p></bio><bio xml:lang="en"><p>Surgery Chair with  the Сourse of Endoscopy and Training Interns for specialization in surgery  of Institute of Professional Education</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каюмов</surname><given-names>Ф. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kayumov</surname><given-names>F. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Каюмов Фарит Амирьянович - доктор медицинских наук, профессор кафедры  гистологии БГМУ</p></bio><bio xml:lang="en"><p>Surgery Chair with  the Сourse of Endoscopy and Training Interns for specialization in surgery  of Institute of Professional Education</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербулатов</surname><given-names>Ш. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbulatov</surname><given-names>Sh. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимербулатов Шамиль Вилевич - доцент кафедры  хирургии с курсом эндоскопии и подготовки интернов хирургического профиля ИПО БГМУ, кандидат медицинских наук.</p><p>450000, Республика Башкортостан, Уфа, ул. Ленина, д. 3, тел. 8 (347) 255-54-57, 255-65-48, e-mail: bulat82@inbox.ru</p></bio><bio xml:lang="en"><p>Surgery Chair with  the Сourse of Endoscopy and Training Interns for specialization in surgery  of Institute of Professional Education</p></bio><email xlink:type="simple">bulat82@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Башкирский  Государственный Медицинский Университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical  University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>27</day><month>01</month><year>2017</year></pub-date><volume>0</volume><issue>2</issue><fpage>17</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тимербулатов В.М., Фаязов Р.Р., Чанышев Б.Ф., Каюмов Ф.А., Тимербулатов Ш.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Тимербулатов В.М., Фаязов Р.Р., Чанышев Б.Ф., Каюмов Ф.А., Тимербулатов Ш.В.</copyright-holder><copyright-holder xml:lang="en">Timerbulatov V.M., Fayazov R.R., Chanyshev B.F., Kayumov F.A., Timerbulatov S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/104">https://www.surgonco.ru/jour/article/view/104</self-uri><abstract><p>Проведенное экспериментальное исследование показало,  что  в  ранние   сроки после  спленэктомии летальность среди  белых  крыс составила 16,25%.  Морфологическое исследование свидетельствует, что у животных определяется постинфекционный гепатит, а также начальная фаза воспаления легочной  ткани. Мезентериальные лимфатические узлы как органы  гемо и иммуноцитопоэза оказались в условиях  выраженного функционального напряжения в ответ на инфицирование организма.</p></abstract><trans-abstract xml:lang="en"><p>Experimental  investigation showed that  through short-term after splenectomy the death rate  of  white  rats  was  16,25%.  Morphological investigation indicates  that  animals have  postinfectious  hepatitis  and   the   first  stage of  pulmonary  tissue   inflammation. Mesenteric lymphatic nodes  as the organs of hemoand immune  cytopoiesis  appear to be under  condition of pronounced functional tension in response to inflammation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>клеточная инфильтрация</kwd><kwd>лейкоциты</kwd><kwd>спленэктомия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cell infiltration</kwd><kwd>leucocytes</kwd><kwd>splenectomy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">A fatal case of overwhelming postsplenectomy infection syndrome developing 10 years after splenectomy / Y. Urata, M. Hasegawa, H. Hasegawa [et al.] // Nihon Rinsho Meneki Gakkai Kaishi. – 1997. – Vol. 20. № 3. – P. 184-190.</mixed-citation><mixed-citation xml:lang="en">A fatal case of overwhelming postsplenectomy infection syndrome developing 10 years after splenectomy / Y. Urata, M. Hasegawa, H. Hasegawa [et al.] // Nihon Rinsho Meneki Gakkai Kaishi. – 1997. – Vol. 20. № 3. – P. 184-190.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Benoist, S. Median and long-term complications of splenectomy / S. Benoist // Ann. Chir. – 2000. – Vol. 125. № 4. – P. 317-324.</mixed-citation><mixed-citation xml:lang="en">Benoist, S. Median and long-term complications of splenectomy / S. Benoist // Ann. Chir. – 2000. – Vol. 125. № 4. – P. 317-324.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Davidson, R.N. Prevention and management of infections in patients without a spleen / R.N. Davidson, R.A. Wall // Clin. Microbiol. Infect. – 2001. – Vol. 7. - № 12. – P. 657-660.</mixed-citation><mixed-citation xml:lang="en">Davidson, R.N. Prevention and management of infections in patients without a spleen / R.N. Davidson, R.A. Wall // Clin. Microbiol. Infect. – 2001. – Vol. 7. - № 12. – P. 657-660.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Dujmovic, F. Post-traumatic asplenia and splenosis / F. Dujmovic // Med. Pregl. – 1993. – Vol. 46. № 7-8. – P. 264-267.</mixed-citation><mixed-citation xml:lang="en">Dujmovic, F. Post-traumatic asplenia and splenosis / F. Dujmovic // Med. Pregl. – 1993. – Vol. 46. № 7-8. – P. 264-267.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Konigswieser, H. Incidence of serious infections after splenectomy in childhood / H. Konigswieser // Prog. Pediatr. Surg. – 1985. – Vol. 18. – P. 173-181.</mixed-citation><mixed-citation xml:lang="en">Konigswieser, H. Incidence of serious infections after splenectomy in childhood / H. Konigswieser // Prog. Pediatr. Surg. – 1985. – Vol. 18. – P. 173-181.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Lethal pneumococcal infection in an 18-monthold girl with splenic hypoplasia and dysgammaglobulinemia / R. Nanan, K. Peters, L. Schrod, H.W. Kreth // Ann. Hematol. – 2001. – Vol. 80. № 11. – P. 674-676.</mixed-citation><mixed-citation xml:lang="en">Lethal pneumococcal infection in an 18-monthold girl with splenic hypoplasia and dysgammaglobulinemia / R. Nanan, K. Peters, L. Schrod, H.W. Kreth // Ann. Hematol. – 2001. – Vol. 80. № 11. – P. 674-676.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
