References

surgonco

Креативная хирургия и онкология

Creative surgery and oncology

2076-30932307-0501

Башкирский государственный медицинский университет

10.24060/2076-3093-2013-0-4-100-108

surgonco-200

Research Article

ОБЗОР ЛИТЕРАТУРЫ

REVIEWS

СОВРЕМЕННОЕ ПРЕДСТАВЛЕНИЕ О РОЛИ ПОСТНАТАЛЬНОГО ИНДУЦИРОВАННОГО НЕОЛИМФАНГИОГЕНЕЗА В ПРОЦЕССЕ МЕТАСТАЗИРОВАНИЯ

MODERN REPRESENTATIONS OF THE ROLE POSTNATAL INDUCED NEOLYMPHANGIOGENESIS IN METASTATIC PROCESS

Кзыргалин

Ш. Р.

Kzyrgalin

Sh. R.

Кзыргалин Шамиль Римович - ассистент кафедры онкологии с курсами онкологии и патологической анатомии ИПО БГМУ.

450000, Респ. Башкортостан, Уфа, ул. Ленина, д. 3, тел. 8 (347) 237-43-58, e-mail: ufa_shamil@rambler.ru

ufa_shamil@rambler.ru

Башкирский государственный медицинский университетРоссияBashkir State Medical UniversityRussian Federation

2013

05022017

04100108

2017

Кзыргалин Ш.Р.

Kzyrgalin S.R.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.surgonco.ru/jour/article/view/200

В статье представлен обзор данных литературы по изучению механизмов образования интратуморальных и перитуморальных лимфатических сосудов при раке, их роли в регионарном и отдаленном метастазировании. Лимфангиогенез сложный многофакторный процесс, изучение которого позволяет уточнить общую картину течения опухолевого процесса.

The article presents an overview of the literature on the study of the mechanisms of formation of intratumoral and peritumoral lymphatic vessels in cancer and their role in regional and distant metastasis. Lymphangiogenesis complex multifactorial process, the study of which helps to clarify the overall flow pattern of the tumor process.

лимфангиогенезракметастазирование

lymphangiogenesiscancermetastasis

References1

Ганцев Ш.Х. Аксиллярный лимфатический аппарат при раке молочной железы. Атлас: издание второе, дополненное, с переводом на английский язык М.: ООО «МИА», 2011. 194 с.: цв.ил.

Achen M.G., Stacker S.A. Tumor lymphangiogenesis and metastatic spread-New players begin to emerge // Int.J.Cancer. – 2006. – P. 1755-1760.

Agarwal B., Saxena R., Morimiya A., Mehrotra S., Badve S. Lymphangiogenesis does not occur in breast cancer // Am.J.Surg.Pathol. – 2005. – Vol. 29. – P. 1449-1455.

Aukland K., Reed R.K. Interstitial-lymphatic mechanisms in the control of extracellular fluid volume // Physiol Rev. – 1993. – Vol. 73. – P. 1-78.

Bader A.A.., Tio J., Petru E., Buhner M., Pfahlberg A., Volkholz H., Tulusan A.H. T1 breast cancer: identification of patients at low risk of axillary lymph node metastases // Breast Cancer Res.Treat. – 2002. – Vol. 76. – P. 11-17.

Baluk P., Fuxe J., Hashizume H. et al. Functionally specialized junctions between endothelial cells of lymphatic vessels // J Exp Med. – 2007. – Vol. 204. – P. 2349-2362.

Banerji S., Ni J., Wang S.X., Clasper S. et al LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan // J.Cell Biol. – 1999. – Vol. 144. – P. 789-801.

Beasley N.J., Prevo R., Banerji S. et al Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer // Cancer Res. – 2002. – Vol. 62. – P. 1315-1320.

Beriwal S., Soran A., Kocer B. et al. Factors that predict the burden of axillary disease in breast cancer patients with a positive sentinel node // Am.J.Clin. Oncol. – 2008. – Vol. 31. – P. 34-38.

Cabioglu N., Yazici M.S., Arun B. et al. CCR7 and CXCR4 as novel biomarkers predicting axillary lymph node metastasis in T1 breast cancer // Clin. Cancer Res. – 2005. – Vol. 11. – P. 5686-5693.

Cady B. Regional lymph node metastases; a singular manifestation of the process of clinical metastases in cancer: contemporary animal research and clinical reports suggest unifying concepts // Ann. Surg.Oncol. – 2007. – Vol. 14. – P. 1790-1800.

Colleoni M., Rotmensz N., Maisonneuve P. et al. Prognostic role of the extent of peritumoral vascular invasion in operable breast cancer // Ann.Oncol. – 2007. – Vol. 18. – P. 1632-1640.

Cueni L.N., Detmar M. The lymphatic system in health and disease // Lymphat Res Biol. – 2008. – Vol. 6. – P. 109-122.

Dadiani M., Kalchenko V., Yosepovich A. et al. Real-time imaging of lymphogenic metastasis in orthotopic human breast cancer // Cancer Res. – 2006. – Vol. 66. – P. 8037-8041.

Dadras S.S., Lange-Asschenfeldt B., Velasco P. et al. lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes // Mod.Pathol. – 2005. – Vol. 18. – P. 1232-1242.

Das S., Skobe M. Lymphatic vessel activation in cancer // Ann.N.Y.Acad.Sci. – 2008. – Vol. 1131. – P. 235-241.

Dobrovolskaia M.A., Kozlov S.V. Inflammation and cancer: when NF-kappaB amalgamates the perilous partnership // Curr.Cancer Drug Targets. – 2005. – Vol. 5. – P. 325-344.

Dua R.S., Gui G.P., Isacke C.M. Endothelial adhesion molecules in breast cancer invasion into the vascular and lymphatic systems // Eur.J.Surg.Oncol. – 2005. – Vol. 31. – P. 824-832.

Fidler I.J., Balch C.M. The biology of cancer metastasis and implications for therapy // Curr Probl Surg. – 1987. – Vol. 24. – P. 129-209.

Gajdos C., Tartter P.I., Bleiweiss I.J. Lymphatic invasion, tumor size, and age are independent predictors of axillary lymph node metastases in women with T1 breast cancers // Ann.Surg. – 1999. – Vol. 230. – P. 692-696.

Gerli R., Solito R., Weber E., Agliano M. Specific adhesion molecules bind anchoring filaments and endothelial cells in human skin initial lymphatics // Lymphology. – 2000. – Vol. 33. – P. 148-157.

Gervasoni J.E., Jr, Sbayi S., Cady B. Role of lymphadenectomy in surgical treatment of solid tumors: an update on the clinical data // Ann.Surg. Oncol. – 2007. – Vol. 14. – P. 2443-2462.

Halin C., Tobler N.E., Vigl B. et al VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes // Blood. – 2007. – Vol. 110. – P. 3158-3167.

Harrell M.I., Iritani B.M., Ruddell A. Tumorinduced sentinel lymph node lymphangiogenesis and increased lymph flow precede melanoma metastasis // Am.J.Pathol. – 2007. – Vol. 170. – P. 774-786.

Isaka N., Padera T.P., Hagendoorn J. et al Peritumor lymphatics induced by vascular endothelial growth factor-C exhibit abnormal function // Cancer Res. – 2004. – Vol. 64. – P. 4400-4404.

Jennbacken K., Vallbo C., Wang W., Damber J.E. Expression of vascular endothelial growth factor C (VEGF-C) and VEGF receptor-3 in human prostate cancer is associated with regional lymph node metastasis // Prostate. – 2005. – P. 110-116.

Kang H., Watkins G., Parr C. et al. Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer // Breast Cancer Res. – 2005. – Vol. 7. – P. R402-R410.

Koyama Y., Kaneko K., Akazawa K. et al. Vascular endothelial growth factor-C and vascular endothelial growth factor-D messenger RNA expression in breast cancer: association with lymph node metastasis // Clin. Breast Cancer. – 2003. – Vol. 4. – P. 354-360.

Lauria R., Perrone F., Carlomagno C. et al. The prognostic value of lymphatic and blood vessel invasion in operable breast cancer // Cancer. – 1995. – Vol. 76. – P. 1772-1778.

Leu A.J., Berk D.A., Lymboussaki A. et al. Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation // Cancer Res. – 2000. – Vol. 60. – P. 4324-4327.

Lin J., Lalani A.S., Harding T.C., Gonzalez M. et al. Inhibition of lymphogenous metastasis using adenoassociated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor // Cancer Res. – 2005. – Vol. 65. – P. 6901-6909.

Marinho V.F., Metze K., Sanches F.S. et al. Lymph vascular invasion in invasive mammary carcinomas identified by the endothelial lymphatic marker D2-40 is associated with other indicators of poor prognosis // BMC.Cancer. – 2008. – Vol. 8. – P. 64.

Mattila M.M., Ruohola J.K., Karpanen T. et al. VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors // Int.J.Cancer. – 2002. – Vol. 98. – P. 946-951.

Mohammed R.A., Ellis I.O., Elsheikh S. et al. Lymphatic and angiogenic characteristics in breast cancer: morphometric analysis and prognostic implications // Breast Cancer Res.Treat. – 2008. – P. 261-273.

Mohammed R.A., Ellis I.O., Lee A.H., Martin S.G. Vascular invasion in breast cancer; an overview of recent prognostic developments and molecular pathophysiological mechanisms // Histopathology. – 2008. – P. 1-9.

Mohammed R.A., Green A., El-Shikh S. et al. Prognostic significance of vascular endothelial cell growth factors -A, -C and -D in breast cancer and their relationship with angioand lymphangiogenesis // Br.J.Cancer. – 2007. – Vol. 96. – P. 1092-1100.

Mohammed R.A., Martin S.G., Gill M.S. et al. Improved methods of detection of lymphovascular invasion demonstrate that it is the predominant method of vascular invasion in breast cancer and has important clinical consequences // Am.J.Surg.Pathol. – 2007. – Vol. 31. – P. 1825-1833.

Morton D.L., Thompson J.F., Cochran A.J. et al. Sentinel-node biopsy or nodal observation in melanoma // N.Engl.J.Med. – 2006. – Vol. 355. – P. 1307-1317.

Muller A., Homey B., Soto H. Ge N. et al Involvement of chemokine receptors in breast cancer metastasis // Nature. – 2001. – Vol. 410. – P. 50-56.

Nakamura Y., Yasuoka H., Tsujimoto M. et al. Lymph vessel density correlates with nodal status, VEGF-C expression, and prognosis in breast cancer // Breast Cancer Res.Treat. – 2005. – Vol. 91. – P. 125-132.

Nakamura Y., Yasuoka H., Tsujimoto M. et al. Clinicopathological significance of vascular endothelial growth factor-C in breast carcinoma with long-term follow-up // Mod.Pathol. – 2003. – Vol. 16. – P. 309-314.

Ozmen V., Karanlik H., Cabioglu N. et al. Factors predicting the sentinel and non-sentinel lymph node metastases in breast cancer // Breast Cancer Res. Treat. – 2006. – Vol. 95. – P. 1-6.

Qian C.N., Berghuis B., Tsarfaty G. et al. Preparing the "soil": the primary tumor induces vasculature reorganization in the sentinel lymph node before the arrival of metastatic cancer cells // Cancer Res. – 2006. – Vol. 66. – P. 10365-10376.

Ran S., Volk L., Hall K., Flister M.J. Lymphangiogenesis and lymphatic metastasis in breast cancer // Pathophysiology. – 2010. – Vol. 17. – P. 229-251.

Rebhun R.B., Lazar A.J., Fidler I.J. et al Impact of sentinel lymphadenectomy on survival in a murine model of melanoma // Clin.Exp.Metastasis. – 2008. – Vol. 25. – P. 191-199.

Roberts N., Kloos B., Cassella M. et al. Inhibition of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2 // Cancer Res. – 2006. – Vol. 66. – P. 2650-2657.

Saaristo A., Veikkola T., Enholm B. et al. Adenoviral VEGF-C overexpression induces blood vessel enlargement, tortuosity, and leakiness but no sprouting angiogenesis in the skin or mucous membranes // FASEB J. – 2002. – Vol. 16. – P. 1041-1049.

Salven P., Mustjoki S., Alitalo R. et al. VEGFR-3 and CD133 identify a population of CD34+ lymphatic/ vascular endothelial precursor cells // Blood. – 2003. – Vol. 101. – P. 168-172.

Schoppmann S.F., Bayer G., Aumayr K. et al. Prognostic value of lymphangiogenesis and lymphovascular invasion in invasive breast cancer // Ann.Surg. – 2004. – Vol. 240. – P. 306-312.

Schoppmann S.F., Fenzl A., Nagy K. et al. VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival // Surgery. – 2006. – Vol. 139. – P. 839-846.

Schoppmann S.F. Lymphangiogenesis, inflammation and metastasis // Anticancer Res. – 2005. – Vol. 25. – P. 4503-4511.

Sleeman J.P., Thiele W. Tumor metastasis and the lymphatic vasculature // Int J Cancer. – 2009. – Vol. 125. – P. 2747-2756.

Sporn M.B. The war on cancer // Lancet. – 1996. – Vol. 347. – P. 1377-1381.

Stacker S.A., Caesar C., Baldwin M.E. et al. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics // Nat.Med. – 2001. – Vol. 7. – P. 186-191.

Swartz M.A., Skobe M. Lymphatic function, lymphangiogenesis, and cancer metastasis // Microsc Res Tech. – 2001. – Vol. 55. – P. 92-99.

Tammela T., Alitalo K. Lymphangiogenesis: molecular mechanisms and future promise // Cell. – 2010. – Vol. 140. – P. 460-476.

Travagli J.P., Atallah D., Mathieu M.C. et al. Sentinel lymphadenectomy without systematic axillary dissection in breast cancer patients: predictors of nonsentinel lymph node metastasis // Eur.J.Surg.Oncol. – 2003. – Vol. 29. – P. 403-406.

Tsai P.W., Shiah S.G., Lin M.T. et al. Upregulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway // J.Biol.Chem. – 2003. – Vol. 278. – P. 5750-5759.

Van den Eynden G.G., van der Auwera I., Van Laere S.J. et al. Distinguishing blood and lymph vessel invasion in breast cancer: a prospective immunohistochemical study // Br.J.Cancer. – 2006. – Vol. 94. – P. 1643-1649.

Van den Eynden G.G., Vandenberghe M.K., van Dam P.J. et al. Increased sentinel lymph node lymphangiogenesis is associated with nonsentinel axillary lymph node involvement in breast cancer patients with a positive sentinel node // Clin.Cancer Res. – 2007. – Vol. 13. – P. 5391-5397.

Van der Auwera I., Van den Eynden G.G. et al. Tumor lymphangiogenesis in inflammatory breast carcinoma: a histomorphometric study // Clin.Cancer Res. – 2005. – Vol. 11. – P. 7637-7642.

Van der Schaft D.W., Pauwels P., Hulsmans S. et al. Absence of lymphangiogenesis in ductal breast cancer at the primary tumor site // Cancer Lett. – 2007. – Vol. 254. – P. 128-136.

Van der Wal B.C., Butzelaar R.M., van der M.S. et al. Axillary lymph node ratio and total number of removed lymph nodes: predictors of survival in stage I and II breast cancer // Eur.J.Surg.Oncol. – 2002. – Vol. 28. – P. 481-489.

Veikkola T., Jussila L., Makinen T. et al. Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice // EMBO J. – 2001. – Vol. 20. – P. 1223-1231.

Viale G., Zurrida S., Maiorano E. et al. Predicting the status of axillary sentinel lymph nodes in 4351 patients with invasive breast carcinoma treated in a single institution // Cancer. – 2005. – Vol. 103. – P. 492-500.

Wang Y., Oliver G. Current views on the function of the lymphatic vasculature in health and disease // Genes Dev. – 2010. – Vol. 24. – P. 2115-2126.

Weidner N. Tumoural vascularity as a prognostic factor in cancer patients: the evidence continues to grow // J.Pathol. – 1998. – Vol. 184. – P. 119-122.

Weinberg R.A. Moving out: Invasion and Metastasis, The biology of cancer // Garland Science. New York: Taylor &Francis Group, LLC; – 2007. – P. 631-634.

Williams C.S., Leek R.D., Robson A.M. et al. Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer 6 // J.Pathol. – 2003. – Vol. 200. – P. 195-206.

Wilting J., Papoutsi M., Christ B. et al. The transcription factor Prox1 is a marker for lymphatic endothelial cells in normal and diseased human tissues // FASEB J. – 2002. – Vol. 16. – P. 1271-1273.

Wong S.Y., Crowley D., Bronson R.T., Hynes R.O. Analyses of the role of endogenous SPARC in mouse models of prostate and breast cancer // Clin. Exp.Metastasis. – 2008. – Vol. 25. – P. 109-118.

Woo C.S., Silberman H., Nakamura S.K. et al. Lymph node status combined with lymphovascular invasion creates a more powerful tool for predicting outcome in patients with invasive breast cancer // Am.J.Surg. – 2002. – Vol. 184. – P. 337-340.

Wulfing P., Kersting C., Buerger H. et al. Expression patterns of angiogenic and lymphangiogenic factors in ductal breast carcinoma in situ // Br.J.Cancer. – 2005. – Vol. 92. – P. 1720-1728.

Yasuoka H., Tsujimoto M., Yoshidome K. et al. Cytoplasmic CXCR4 expression in breast cancer: induction by nitric oxide and correlation with lymph node metastasis and poor prognosis // BMC.Cancer. – 2008. – Vol. 8. – P. 340.

The authors declare that there are no conflicts of interest present.