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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2017-7-1-4-10</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-204</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ВОЗМОЖНОСТИ ИНТЕРВЕНЦИОННОЙ КОРРЕКЦИИ КРИТИЧЕСКОГО АОРТАЛЬНОГО СТЕНОЗА: СOВРЕМЕННОЕ СОСТОЯНИЕ ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ</article-title><trans-title-group xml:lang="en"><trans-title>POSSIBILITIES OF INTERVENTIONAL CORRECTION OF CRITICAL AORTIC STENOSIS: CONTEMPORARY STATE OF PROBLEM AND PERSPECTIVES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Амзаев</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Amzaev</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры госпитальной терапии медицинского факультета;</p><p>врач РЭДиЛ,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Research Assistant of Hospital Therapy Department, Medicine Faculty,</p><p>Physician at Endovascular Methods of Diagnosis and Treatment Department,</p><p>Saint-Petersburg</p></bio><email xlink:type="simple">Amzaev@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сергеев</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sergeev</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач РЭДиЛ, </p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Physician of Endovascular Methods of Diagnosis and Treatment Department,</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сухов</surname><given-names>В. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Sukhov</surname><given-names>V. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н, профессор, врач РЭДиЛ,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Professor, Physician at Endovascular Methods of Diagnosis and Treatment Department,</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шлойдо</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shloydo</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., зав. отделением РЭДиЛ,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Candidate of Medical Sciences, Head of Endovascular Methods of Diagnosis and Treatment Department,</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Обрезан</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Obrezan</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н, профессор, зав. кафедрой госпитальной терапии, Медицинский факультет;</p><p>главный врач ММЦ «СОГАЗ»,</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Chair of Hospital Therapy Department, Medicine Faculty;</p><p>Chief of International Medical Centre “SOGAZ”,</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский Государственный Университет;&#13;
СПб ГБУЗ “Городская многопрофильная больница № 2”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State University;&#13;
Saint-Petersburg State Budgetary Health Institution “City Multi-Field Hospital №2”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>СПб ГБУЗ “Городская многопрофильная больница № 2”</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State Budgetary Health Institution “City Multi-Field Hospital №2”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Санкт-Петербургский Государственный Университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>22</day><month>04</month><year>2017</year></pub-date><volume>7</volume><issue>1</issue><fpage>4</fpage><lpage>10</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Амзаев С.А., Сергеев А.С., Сухов В.К., Шлойдо Е.А., Обрезан А.Г., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Амзаев С.А., Сергеев А.С., Сухов В.К., Шлойдо Е.А., Обрезан А.Г.</copyright-holder><copyright-holder xml:lang="en">Amzaev S.A., Sergeev A.S., Sukhov V.K., Shloydo E.A., Obrezan A.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/204">https://www.surgonco.ru/jour/article/view/204</self-uri><abstract><p>В данной статье рассмотрены вопросы этиологии и патогенеза развития аортального стеноза, клиническая оценка степеней тяжести, основанная на выраженности симптомов при декомпенсации аортального порока и эхокардиографических параметрах, и современные методы коррекции аортального стеноза. Общепризнанным «золотым стандартом» в лечении аортального стеноза является протезирование клапана. Однако операция протезирования аортального клапана у пациентов старшей возрастной группы с различной сопутствующей патологией сопряжена с высоким уровнем периоперационных осложнений. Альтернативными способами лечения аортального стеноза являются метод баллонной вальвулопластики и транскатетерная имплантация аортального клапана. Анализ собственного опыта применения данных малоинвазивных методов коррекции критического аортального стеноза убедительно демонстрирует снижение периоперационных рисков у пациентов старшей возрастной группы с сопутствующей патологией и убеждает в необходимости госпитализации коморбидных возрастных пациентов со значительными степенями стеноза аортального клапана и продвинутыми степенями сердечной недостаточности в специализированных центрах, где возможен комплексный подход в лечении данной патологии, который приводит к улучшению результатов лечения и благоприятному прогнозу у этой сложной категории пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The paper studies the issues of aortic stenosis etiology and pathogenesis, clinical assessment of severity based on the distinct symptoms of decompensated aortic defect and echocardiographic measures, and modern methods of aortic stenosis correction. Valve replacement is well known as the «gold standard» in the treatment of aortic stenosis. However, the older-age-group patients with different attendant pathologies are likely to have re-operative complications during the valve replacement operation. The alternative methods of aortic stenosis treating are balloon valvuloplasty and transcatheter implantation of the aortic valve. Analyzing the experience of using the minimally invasive methods of critical aortic stenosis correction convincingly shows reduction of re-operative danger among older-age-group patients with different attendant pathologies and persuades to hospitalize old-aged comorbid patients with significant degrees of aortic valve stenosis and advanced degrees of heart failure to special medical centers. There patients can get an integrated approach to the treatment of this disease that leads to improving treatment results and favorable prognosis in this challenging group of patients.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аортального клапана стеноз</kwd><kwd>факторы риска</kwd><kwd>баллонная дилатация</kwd><kwd>аортального клапана транскатетерная имплантация</kwd><kwd>коморбидность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>aortic valve stenosis</kwd><kwd>risk factors</kwd><kwd>balloon dilatation</kwd><kwd>transcatheter aortic valve replacement</kwd><kwd>comorbidity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Leopold JA. Cellular mechanisms of aortic valve calcification. Circ Cardiovasc Interv. 2012;(5):605-614. DOI: 10.1161/CIRCINTERVENTIONS.112.971028.</mixed-citation><mixed-citation xml:lang="en">Leopold JA. 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