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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2017-7-4-32-37</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-266</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>РЕЗУЛЬТАТЫ ИЗУЧЕНИЯ ВЗАИМОСВЯЗИ ГРУППЫ КРОВИ  С РАЗВИТИЕМ КОЛОРЕКТАЛЬНОГО РАКА</article-title><trans-title-group xml:lang="en"><trans-title>THE RESULTS OF THE STUDY OF BLOOD GROUP AND COLORECTAL CANCER INTERRELATION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6156-0958</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Керимов</surname><given-names>Р. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kerimov</surname><given-names>Rasim A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Керимов Расим Азат-оглы – магистр медицины, PhD докторант Международного Казахско-Турецкого университета им. Х.А. Ясави.</p><p>Туркестан, пр. Б. Саттарханова, 29. </p></bio><bio xml:lang="en"><p>Kerimov Rasim Azat-ogly – Master of Medicine, PhD of Yasavi Kh.A. International Kazakh-Turkish University.</p><p>29 Sattarkhanov avenue, Turkestan.</p></bio><email xlink:type="simple">kir-2004@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2556-2360</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сексенбаев</surname><given-names>Б. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Seksenbaev</surname><given-names>Bakhytzhan D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сексенбаев Бахытжан Дерибсалиевич – доктор медицинских наук, профессор Южно-казахстанской государственной фармацевтической академии.</p><p>160019, Шымкент, пл. Аль-Фараби, 1. </p></bio><bio xml:lang="en"><p>Seksenbaev Bakhytzhan Deribsalievich – Doctor of Medical Sciences, Professor of Sourthen-Kazakh State Pharmaceutical Academy.</p><p>1 Al-Farabi square, Shymkent, 160019.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галимов</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Galimov</surname><given-names>Oleg V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галимов Олег Владимирович – д.м.н., профессор, заведующий кафедрой хирургических болезней и новых технологий с курсом ИДПО ФГБОУ ВО БГМУ Минздрава России.</p><p>450008, Уфа, ул. Ленина, 3.</p></bio><bio xml:lang="en"><p>Galimov Oleg Vladimirovich – Doctor of Medical Sciences, Head of the Surgical Diseases and New Technologies with the Course of Additional Professional Education Institution of Federal State Budgetary Educational Institution of Higher Education Bashkir State Medical University, Ministry of Healthcare of Russian Federation. </p><p> 3 Lenin st., Ufa, 450008.</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3949-2543</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нурмашев</surname><given-names>Б. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Nurmashev</surname><given-names>Bekaydar K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нурмашев Бекайдар Калдыбаевич - доктор PhD, ассоциированный профессор Южно-казахстанской государственной фармацевтической академии.</p><p>160019, Шымкент, пл. Аль-Фараби, 1. </p></bio><bio xml:lang="en"><p>Nurmashev Bekaydar Kaldybaevich – PhD, Associate Professor of Sourthen-Kazakh State Pharmaceutical Academy.</p><p>1 Al-Farabi square, Shymkent, 160019.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5387-3476</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жантеев</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhanteev</surname><given-names>Murat E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жантеев Мурат Ендыбаевич – к.м.н., доцент Международного Казахско-Турецкого университета им. Х.А. Ясави.</p><p>Туркестан, пр. Б. Саттарханова, 29. </p></bio><bio xml:lang="en"><p>Zhanteev Murat Endybaevich – Candidate of Medical Sciences, Associate Professor of International Kazakh-Turkish University.</p><p>29 Sattarkhanov avenue, Turkestan.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Международный Казахско-Турецкий университет им. Х.А. Ясави.</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>Akhmet Yassawi International Kazakh-Turkish University.</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Южно-казахстанская государственная фармацевтическая академия.</institution><country>Казахстан</country></aff><aff xml:lang="en"><institution>South Kazakhstan State Pharmaceutical Academy.</institution><country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>09</day><month>12</month><year>2017</year></pub-date><volume>7</volume><issue>4</issue><fpage>32</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Керимов Р.А., Сексенбаев Б.Д., Галимов О.В., Нурмашев Б.К., Жантеев М.Е., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Керимов Р.А., Сексенбаев Б.Д., Галимов О.В., Нурмашев Б.К., Жантеев М.Е.</copyright-holder><copyright-holder xml:lang="en">Kerimov R.A., Seksenbaev B.D., Galimov O.V., Nurmashev B.K., Zhanteev M.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/266">https://www.surgonco.ru/jour/article/view/266</self-uri><abstract><sec><title>Введение</title><p>Введение. По данным ряда исследований обнаружены корреляции между группами крови, раком желудка и поджелудочной железы. Однако очевидных связей между колоректальным раком и группами крови установлено не было. В этой связи основной целью данной работы является анализ ассоциации между колоректальным раком и группами крови среди населения Южного Казахстана.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Исследование проводилось в два этапа. На первом этапе была рассчитана доля каждой группы крови (по системам AB0 и Rh) среди 87 329 доноров Центра переливания крови г. Шымкент. На втором этапе проведен ретроспективный анализ историй болезней пациентов с колоректальным раком Областного онкологического диспансера г. Шымкент. Каждая история анализировалась по таким признакам, как возраст пациента, пол, группа крови (по системам AB0 и Rh), локализация колоректального рака, стадия заболевания.</p></sec><sec><title>Результаты</title><p>Результаты. Установлено следующее распределение групп крови у населения Южно-Казахстанской области:  0 – 31,76%, A – 31,3%, B – 27,18%, AB – 9,76%, Rh (+) – 95,09%, Rh (–) – 4,91%. Взаимосвязь между группами крови и заболеванием оценивалась как несущественная (V=0,081 и V=0,073 для AB0 и Rh соответственно). Анализ связи группы крови и рака левой ободочной кишки демонстрирует слабую корреляцию (χ2 (3)=8,233, p=0,041). Взаимосвязь между группой крови системы AB0 и опухолью данной локализации оценивалась как средняя (V=0,265).</p></sec><sec><title>Заключение</title><p>Заключение. Результаты, которые мы получили, не предполагают наличие корреляции между группами крови и колоректальным раком. Однако выявлена слабая корреляция между онкологическим поражением левой ободочной кишки и I(0) группой крови в исследуемой популяции. </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Several studies showed a correlation between blood groups and cancer of the stomach and the pancreas. However, the obvious links between colorectal cancer and blood groups have been found. In this context, the main objective of this work is to analyze the association between colorectal cancer and blood groups among the population of Southern Kazakhstan.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study was conducted in two phases. The first phase calculated the share of each blood group (according to ABO and Rh systems) among 87329 donors of Blood Transfusion Centre (city of Shymkent). The second phase of the retrospective analysis of disease history in patients with colorectal cancer, according to the Regional Oncology Center (city of Shymkent). Each story is reviewed, based on such factors as patient’s age, gender, blood group (according to ABO and Rh systems), localization of colorectal cancer, stage of the disease.</p></sec><sec><title>Results</title><p>Results. The research defined the following distribution of blood groups for the population of South-Kazakhstan region:  0 - 31.76%, A - 31.3%, B - 27.18%, AB - 9.76%, Rh (+/-)-95.09%, Rh (-)-4.91%. The level of interconnection between blood groups and disease was assessed as insignificant (V = 0.081 and V = 0.073 for ABO and Rh, respectively). Analysis of the relation of blood group and the left colon cancer demonstrates week correlation (χ2 (3) = 8.233, p = 0.041). The strength of the relation between ABO blood group and the tumor of this localization was assessed as average (V = 0.265).</p></sec><sec><title>Conclusion</title><p>Conclusion. The received results do not imply a correlation between blood groups and colorectal cancer. However, there is weak correlation regarding the intercorrelation of cancer lesions of the left colon and I(0) blood group in the study population. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальные новообразования</kwd><kwd>ободочной кишки новообразования</kwd><kwd>прямой кишки новообразования</kwd><kwd>группы крови</kwd><kwd>система АВО</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colorectal neoplasms</kwd><kwd>colonic neoplasms</kwd><kwd>rectal neoplasms</kwd><kwd>abo bloodgroup system</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Risch H.A., Lu L., Wang J., Zhang W., Ni Q., Gao Y.T., et al. ABO blood group and risk of pancreatic cancer: a study in Shanghai and meta-analysis. Am J Epidemiol. 2013;177(12):1326–37. 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