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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2018-8-3-243-247</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-339</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Случай гигантской кондиломы Бушке — Левенштейна</article-title><trans-title-group xml:lang="en"><trans-title>A Case of the Giant Buschke — Loewenstein Tumour</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3299-1924</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белобородов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Beloborodov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор, зав. кафедрой общей хирургии, тел. +7 (3952) 24-38-25, Россия, 664003, Иркутск, ул. Красного Восстания, 1; Россия, 664046, Иркутск, ул. Байкальская, 118.</p></bio><bio xml:lang="en"><p>Doctor of Medical Sciences, Professor, Head of the Department of General Surgery, tel.: +7 (3952) 24-38-25, 1 Krasnogo Vosstania str., Irkutsk, 664003, Russian Federation; 118 Baykalskaya str., Irkutsk, 664046, Russian Federation.</p></bio><email xlink:type="simple">bva555@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3285-5559</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobev</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-уролог отделения урологии, ассистент кафедры общей хирургии, тел. +7 (3952) 22-99-59, Россия, 664003, Иркутск, ул. Красного Восстания, 1; Россия, 664046, Иркутск, ул. Байкальская, 118.</p></bio><bio xml:lang="en"><p>Urologist at the Department of Urology, Assistant lecturer of the Department of General Surgery, tel. +7 (3952) 22-99-59, 1 Krasnogo Vosstania str., Irkutsk, 664003, Russian Federation; 118 Baykalskaya str., Irkutsk, 664046, Russian Federation.</p></bio><email xlink:type="simple">terdenecer@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаракшинов</surname><given-names>Б. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharakshinov</surname><given-names>B. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-уролог отделения урологии, тел. +7 (3952) 22-99-59, Россия, 664046, Иркутск, ул. Байкальская, 118.</p></bio><bio xml:lang="en"><p>Urologist at the Department of Urology, tel. +7 (3952) 22-99-59, 118 Baykalskaya str., Irkutsk, 664046, Russian Federation.</p></bio><email xlink:type="simple">uro.igkb1@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Иркутский государственный медицинский университет; Иркутская городская клиническая больница № 1.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk State Medical University; Irkutsk City Clinical Hospital No. 1.</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Иркутская городская клиническая больница № 1.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Irkutsk City Clinical Hospital No. 1.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>26</day><month>01</month><year>2019</year></pub-date><volume>8</volume><issue>3</issue><fpage>243</fpage><lpage>247</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Белобородов В.А., Воробьев В.А., Шаракшинов Б.К., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Белобородов В.А., Воробьев В.А., Шаракшинов Б.К.</copyright-holder><copyright-holder xml:lang="en">Beloborodov V.A., Vorobev V.A., Sharakshinov B.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/339">https://www.surgonco.ru/jour/article/view/339</self-uri><abstract><sec><title>Введение</title><p>Введение. Опухоль Бушке — Левенштейна описана впервые в 1925 году как редко встречающаяся гигантская кондилома. Главной причиной возникновения этой патологии считается вирус папилломы человека, который внедряется в организм при благоприятных условиях. Возбудитель может передаваться половым путем. Новообразование обычно локализуется в аногенитальной области. Злокачественная трансформация и распространение его на половой член еще более редки.</p></sec><sec><title>Цели и задачи</title><p>Цели и задачи. Опухоль Бушке — Левенштейна является редкой патологией, особенности течения и лечения которого представляют существенный интерес для врачей-урологов.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В этой статье представлен клинический случай злокачественной гигантской кондиломы Бушке — Левенштейна с первичной локализацией на передней брюшной стенке и распространением на гениталии у мужчины 42 лет без сопутствующего иммунодефицита и урогенитальных инфекций. Анамнез постепенно прогрессировавшего заболевания при отсутствии какого-либо лечения составил более 10 лет. При дооперационном цитологическом исследовании биоптата не было выявлено признаков злокачественного преобразования. Пациенту было выполнено одномоментное удаление всех очагов новообразования и реконструктивно-пластическая операция с использованием кожных лоскутов.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Очаги опухоли удалены целиком без нарушений хирургических границ. При послеоперационном гистологическом исследовании выявили мелкие очаги плоскоклеточной карциномы в удаленных тканях. При послеоперационном наблюдении в течение 6 месяцев после операции не выявлено признаков рецидива заболевания.</p></sec><sec><title>Заключение</title><p>Заключение. Опухоль Бушке — Левенштейна редко сопровождается малигнизацией. Тем не менее необходимо тщательное соблюдение онкологической настороженности. После удаления крупного новообразования особое значение в послеоперационном качестве жизни имеет выбор реконструктивно-пластического вмешательства. Для профилактики рецидива целесообразно проведение иммунотерапии в послеоперационном периоде.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The Buschke — Loewenstein tumour was described for the first time in 1925 as a rare giant condyloma. The main cause of this pathology is the human papillomavirus, which is introduced into the body under certain conditions. This pathogen can be transmitted sexually. The neoplasm is usually localised in the anogenital region. Malignant transformation and its spread to the penis are even more rare.</p></sec><sec><title>Aims</title><p>Aims. The Buschke — Loewenstein tumour is a rare pathology, whose course and treatment features are of considerable interest to urologists.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. This article presents a clinical case of the malignant giant Buschke — Loewenstein tumour with primary localisation on the anterior abdominal wall and spreading to the genitals of a 42-year-old man without accompanying immunodeficiency or urogenital infections. The anamnesis of the gradually progressive disease in the absence of any treatment was more than 10 years. When preoperative cytological examination of the biopsy did not reveal signs of malignant transformation, the patient underwent simultaneous removal of all neoplasm foci and reconstructive plastic surgery using skin grafts.</p></sec><sec><title>Results and Discussion</title><p>Results and Discussion. The foci of the tumour were removed entirely without disturbing surgical boundaries. A postoperative histological examination revealed small foci of squamous cell carcinoma in remote tissues. A postoperative observation conducted six months following surgery revealed no signs of recurrence of the disease.</p></sec><sec><title>Conclusion</title><p>Conclusion. Buschke-Loewenstein tumours are rarely accompanied by malignancy. Nevertheless, oncological vigilance forms a necessary element of postoperative procedures. Following removal of a large neoplasm, the choice of reconstructive plastic surgery is of particular significance for postoperative quality of life. For the prevention of relapse, it is advisable to conduct immunotherapy in the postoperative period.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>опухоль Бушке — Левенштейна</kwd><kwd>папилломавирусные инфекции</kwd><kwd>половые органы</kwd><kwd>остроконечная кондилома</kwd><kwd>восстановительные хирургические операции</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Buschke — Loewenstein tumour</kwd><kwd>papillomavirus infections</kwd><kwd>genitalia</kwd><kwd>condylomata acuminata</kwd><kwd>reconstructive surgical procedures</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Spinu D., Rădulescu A., Bratu O., Checheriţă I.A., Ranetti A.E., Mischianu D. Giant condyloma acuminatum — Buschke — Lowenstein disease — a literature review. Chirurgia (Bucur). 2014;109(4): 445–50. 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