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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2018-8-4-268-272</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-345</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Роль бляшек, богатых липидами, в результатах имплантации стентов с лекарственным покрытием  у пациентов с ишемической болезнью сердца</article-title><trans-title-group xml:lang="en"><trans-title>Role of Lipid-Rich Plaques in Outcomes of Drug-Eluting Stent Implantation in Patients with Coronary Artery Disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мустафина</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mustafina</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мустафина Ирина Аликовна — кандидат медицинских наук, доцент кафедры пропедевтики внутренних болезней.</p><p>450008, Уфа, ул. Ленина, 3, тел.:+79279513980</p></bio><bio xml:lang="en"><p>Mustafina Irina Alikovna — Candidate of Medical Sciences, Associate Professor at the Department of Propaedeutics of Internal Diseases.</p><p>3 Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">iramust@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5527-4477</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ишметов</surname><given-names>В. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Ishmetov</surname><given-names>V. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ишметов Владимир Шамилевич — доктор медицинских наук, профессор кафедры госпитальной хирургии, заведующий отделением рентгенэндоваскулярной диагностики и лечения.</p><p>450008, Уфа, ул. Ленина, 3</p></bio><bio xml:lang="en"><p>Ishmetov Vladimir Shamilevich — Doctor of Medical Sciences, Professor at the Department of Hospital Surgery, Head of the Department of Endovascular Diagnostics and Treatment.</p><p>3 Lenin str., Ufa, 450008</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2125-4897</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлов</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlov</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павлов Валентин Николаевич — доктор медицинских наук, член-корреспондент РАН, профессор, ректор, заведующий кафедрой урологии с курсом ИДПО.</p><p>450008, Уфа, ул. Ленина, 3</p></bio><bio xml:lang="en"><p>Pavlov Valentin Nikolaevich — Doctor of Medical Sciences, Corresponding Member of the Russian Academy of Sciences, Rector, Head of the Department of Urology with the Course of Additional Professional Education.</p><p>3 Lenin str., Ufa, 450008</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2386-6707</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Загидуллин</surname><given-names>Н. Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Zagidullin</surname><given-names>N. Sh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Загидуллин Науфаль Шамилевич — доктор медицинских наук, профессор кафедры пропедевтики внутренних болезней.</p><p>450008, Уфа, ул. Ленина, 3</p></bio><bio xml:lang="en"><p>Zagidullin Naufal Shamilevich — Doctor of Medical Sciences, Professor at the Department of Propaedeutics of Internal Disease.</p><p>3 Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">znaufal@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>21</day><month>03</month><year>2019</year></pub-date><volume>8</volume><issue>4</issue><fpage>268</fpage><lpage>272</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мустафина И.А., Ишметов В.Ш., Павлов В.Н., Загидуллин Н.Ш., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Мустафина И.А., Ишметов В.Ш., Павлов В.Н., Загидуллин Н.Ш.</copyright-holder><copyright-holder xml:lang="en">Mustafina I.A., Ishmetov V.S., Pavlov V.N., Zagidullin N.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/345">https://www.surgonco.ru/jour/article/view/345</self-uri><abstract><sec><title>Введение</title><p>Введение. Влияние липидного содержания атеросклеротической бляшки на результаты стентирования пораженной артерии требует уточнения. Целью данного исследования явилось изучение результатов стентирования у пациентов с бляшками, богатыми липидами, и нелипидными бляшками после имплантации стентов с лекарственным покрытием методом оптической когерентной томографии (ОКТ).</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследование были включены 43 пациента, из которых 26 пациентов были в группе с бляшками, богатыми липидами, и 17 — в группе с нелипидными бляшками. Степень содержания липидов в бляшке была оценена с помощью ОКТ. Была рассчитана доля снимков, содержащих малаппозицию, протрузию ткани, диссекцию и тромб в соответствии с установленными критериями.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. В группе бляшек, богатых липидами, была выше частота сахарного диабета 2-го типа. Данные ОКТ, проведенного после ЧКВ, показали, что в группе бляшек, богатых липидами, была выше доля малаппозиции стратов и протрузий ткани. В группе бляшек, богатых липидами, по сравнению с нелипидными бляшками чаще встречался остаточный тромб.</p></sec><sec><title>Заключение</title><p>Заключение. Бляшки, богатые липидами, ассоциированы с более частой малаппозицией, протрузией ткани и тромбом после стентирования, что свидетельствует о связи типа атеросклеротического поражения артерии и неоптимальных результатов установки стентов.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The role of the lipid content of atherosclerotic plaques in outcomes of stenting is in need of further investigation. This study is aimed at assessing the outcomes in patients with lipid-rich and non-lipid-rich plaques following the drug-eluting stent (DES) implantation using the method of optical coherence tomography (OCT).</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The total of 43 examined patients included 26 patients in the lipid-rich plaque group and 17 in the non-lipid-rich plaque group. The characteristics of plaques were examined by OCT. The percentages of sites presenting malapposition, tissue protrusion, dissection and thrombus were calculated according to established criteria.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The percentage of patients with the type 2 diabetes, the percentage of malapposition and tissue protrusion were all higher in the lipid-rich plaque group. Residual thrombus was more frequent in the lipid-rich plaque group in comparison with the non-lipid -rich plaque group.</p></sec><sec><title>Conclusions</title><p>Conclusions. Lipid-rich plaques correlate with a higher incidence of malapposition, tissue protrusion, and thrombus following the stenting procedure, thus confirming the link between the atherosclerotic lesion type and suboptimal stenting outcomes.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>атеросклеротическая бляшка</kwd><kwd>визуализация</kwd><kwd>оптическая когерентная томография</kwd><kwd>стенты с лекарственным покрытием</kwd><kwd>сиролимус</kwd><kwd>чрескожное коронарное вмешательство</kwd></kwd-group><kwd-group xml:lang="en"><kwd>myocardial ischemia</kwd><kwd>arteriosclerotic plaque</kwd><kwd>visualization</kwd><kwd>optical coherence tomography</kwd><kwd>drug-eluting stents</kwd><kwd>sirolimus</kwd><kwd>percutaneous coronary intervention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Xie Z., Tian J., Ma L., Du H., Dong N., Hou J., et al. 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