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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2019-9-4-311-316</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-441</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRIEF COMMUNICATIONS</subject></subj-group></article-categories><title-group><article-title>Диагностика и терапия аденом гипофиза</article-title><trans-title-group xml:lang="en"><trans-title>Diagnosis and Treatment of Pituitary Adenomas</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6149-5460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бейлерли</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Beylerli</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бейлерли Озал Арзуман оглы — аспирант кафедры урологии с курсом ИДПО</p></bio><bio xml:lang="en"><p>Beylerli Ozal Arzuman — Post-graduate student of the Department of Urology with the Course of Additional Professional Education</p><p>3 Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">obeylerli@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Shiguang</surname><given-names>Zhao</given-names></name><name name-style="western" xml:lang="en"><surname>Shiguang</surname><given-names>Zhao</given-names></name></name-alternatives><bio xml:lang="ru"><p>Shiguang Zhao — профессор, зав. кафедрой нейрохирургии</p></bio><bio xml:lang="en"><p>Shiguang Zhao — Professor, Head of the Department of Neurosurgery</p><p>157 Baojian Rd, Nangang Qu, Haerbin Shi, Heilongjiang Sheng, 150081, China</p></bio><email xlink:type="simple">guangsz@hotmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4965-0835</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гареев</surname><given-names>И. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Gareev</surname><given-names>I. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гареев Ильгиз Фанилевич — аспирант кафедры нейрохирургии и медицинской реабилитации с курсом ИДПО</p></bio><bio xml:lang="en"><p>Gareev Ilgiz Fanilevich — Post-graduate student of the Department of Neurosurgery and Medical Rehabilitation with the Course of Additional Professional Education</p><p>3 Lenin str., Ufa, 450008</p></bio><email xlink:type="simple">ilgiz_gareev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Xin</surname><given-names>Chen</given-names></name><name name-style="western" xml:lang="en"><surname>Xin</surname><given-names>Chen</given-names></name></name-alternatives><bio xml:lang="ru"><p>Xin Chen — ассистент кафедры нейрохирургии, врач-фармаколог</p></bio><bio xml:lang="en"><p>Xin Chen — Assistant lecturer of the Department of Neurosurgery, Pharmacologist</p><p>157 Baojian Rd, Nangang Qu, Haerbin Shi, Heilongjiang Sheng, 150081, China</p></bio><email xlink:type="simple">chenxin_tracy@yeah.net</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет&#13;
450008, Уфа, ул. Ленина, 3</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Харбинский медицинский университет&#13;
Китай, 150081, Хэйлунцзян, Харбин, Наньган, Баоцзянь-роуд, 157</institution><country>Китай</country></aff><aff xml:lang="en"><institution>Harbin Medical University</institution><country>China</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>24</day><month>01</month><year>2020</year></pub-date><volume>9</volume><issue>4</issue><fpage>311</fpage><lpage>316</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бейлерли О.А., Shiguang Z., Гареев И.Ф., Xin C., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Бейлерли О.А., Shiguang Z., Гареев И.Ф., Xin C.</copyright-holder><copyright-holder xml:lang="en">Beylerli O.A., Shiguang Z., Gareev I.F., Xin C.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/441">https://www.surgonco.ru/jour/article/view/441</self-uri><abstract><p>Аденомы гипофиза являются одними из наиболее распространенных первичных внутричерепных опухолей.Обычно доброкачественные, на их долю приходится 10–15 % всех внутричерепных новообразований. Подразделяются на 2 подгруппы: макроаденомы (&gt;1 см) и микроаденомы (&lt;1 см). Около 30 % аденом гипофиза не продуцируют гормоны. В остальных случаях опухоли могут продуцировать все гормоны передней доли гипофиза и тем самым вызывать эндокринные заболевания. Сжатие гипофиза, смежных черепных нервов и структур головного мозга может привести к недостаточности самой железы, недостаточности черепных нервов и другим неврологическим расстройствам. Нарушения зрения, как правило, с битемпоральной гемианопсией, являются одним из наиболее распространенных первичных симптомов. Диагностика заболевания требует междисциплинарного подхода. За исключением пролактином, трансназальная транссфеноидальная резекция требуется при всех симптоматических аденомах гипофиза. Пролактиномы очень хорошо поддаются лечению агонистами дофамина. В случае недостаточности гипофиза начало адекватной замены гормонов имеет большое значение. Долгосрочное наблюдение является неотъемлемой частью концепции терапии. В данном обзоре мы рассмотрим диагностические критерии выявления различных форм аденом гипофиза и современные методы их терапии.</p></abstract><trans-abstract xml:lang="en"><p>Pituitary adenomas are among the most common primary intracranial tumours. They are predominantly benign and account for 10–15 % of all intracranial neoplasms. These tumours are divided into two subgroups: macroadenomas (&gt; 1 cm) and microadenomas (&lt;1 cm). About 30% of pituitary adenomas do not produce hormones. In other cases tumours can produce any of the hormones of the anterior pituitary gland and thus cause endocrine disorders. Compression of the pituitary gland, adjacent cranial nerves and brain structures can lead to gland failure, cranial nerve deficit and other neurological disorders. Visual impairment, usually with bitemporal hemianopia, is one of the most common primary symptoms. Diagnosis of the disease requires an interdisciplinary approach. Transnasal transsphenoidal resection is indicated for all patients with symptomatic pituitary adenomas except prolactinomas. Prolactinomas respond very well to treatment with dopamine agonists. In cases of pituitary insufficiency a timely start of adequate hormone replacement therapy is important. Long-term follow-up is an integral part of the treatment concept. In this review we examine the current diagnostic criteria and treatment methods for various forms of pituitary adenomas.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аденома гипофиза</kwd><kwd>пролактинома</kwd><kwd>пролактин</kwd><kwd>соматотропин</kwd><kwd>дифференциальная диагностика</kwd><kwd>неврологическая диагностика</kwd><kwd>гипофизэктомия</kwd><kwd>радиотерапия гипофиза</kwd><kwd>послеоперационные осложнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pituitary adenoma</kwd><kwd>prolactinoma</kwd><kwd>prolactin</kwd><kwd>somatotropin</kwd><kwd>differential diagnosis</kwd><kwd>neurologic diagnosis</kwd><kwd>hypophysectomy</kwd><kwd>pituitary radiotherapy</kwd><kwd>postoperative complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Lloyd R.V., Osamura R.Y., Klöppel G., Rosai J. (eds.) WHO classification of tumours of endocrine organs. 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