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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2020-10-1-52-57</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-471</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>К вопросу о ранней диагностике базальноклеточного рака (описание клинического случая)</article-title><trans-title-group xml:lang="en"><trans-title>On the Early Diagnosis of Basal Cell Carcinoma (Case Description)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1070-5229</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гомберг</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gomberg</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гомберг Михаил Александрович — доктор медицинских наук, профессор, главный научный сотрудник.</p><p>119071, Москва, Ленинский проспект, 17, тел.: 8 916 5051991</p></bio><bio xml:lang="en"><p>Gomberg Mikhail Alexandrovich — Dr. Sci. (Med.), Prof., Chief Researcher</p><p>17 Leninsky Avenue, Moscow, 119071, tel.: 8 916 5051991</p></bio><email xlink:type="simple">magomberg@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8674-2803</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хисматуллина</surname><given-names>З. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khismatullina</surname><given-names>Z. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хисматуллина Зарема Римовна — доктор медицинских наук, профессор, заведующая кафедрой дерматовенерологии с курсами дерматовенерологии и косметологии ИДПО.</p><p>450008, Уфа, ул. Ленина, 3, тел.: 8 987 2554301</p></bio><bio xml:lang="en"><p>Khismatullina Zarema Rimovna — Dr. Sci. (Med.), Prof., Head of the Department, Department of Dermatovenerology with courses of Dermatovenerology and Cosmetology for Advanced Professional Training.</p><p>3 Lenin str., Ufa, 450008, tel.: 8 987 2554301</p></bio><email xlink:type="simple">hzr07@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7807-9690</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Файзулин</surname><given-names>Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Fayzulin</surname><given-names>N. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Файзулин Наиль Камилович — врач-дерматовенеролог.</p><p>450008, Уфа, ул. Ленина, 3, тел.: 8 917 4241112</p></bio><bio xml:lang="en"><p>Fayzulin Nail Kamilovich — dermatovenerologist.</p><p>42 Industrialnoe Shosse, Ufa, 450030, tel.: 8 917 4241112</p></bio><email xlink:type="simple">fanaka@live.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0605-7879</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титоян</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Titoyan</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Титоян Арман Мартинович — заведующий Муниципальным межрайонным онкологическим центром, онколог.</p><p>450099, Уфа, ул. Маршала Жукова, 4/1, тел.:+7 917 7723444</p></bio><bio xml:lang="en"><p>Titoyan Arman Martinovich — Director, Municipal Interdistrict Oncology Centre, oncologist. </p><p>4/1 Marshala Zhukova str., Ufa, 450099, tel.: + 7 917 7723444</p></bio><email xlink:type="simple">arm-tit@rambler.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Московский научно-практический центр дерматовенерологии и косметологии</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow Scientific and Practical Centre of Dermatovenerology and Cosmetology</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Республиканский кожно-венерологический диспансер № 1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Dermatovenerologic Dispensary No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Поликлиника № 43</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Polyclinic No. 43</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>14</day><month>05</month><year>2020</year></pub-date><volume>10</volume><issue>1</issue><fpage>52</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гомберг М.А., Хисматуллина З.Р., Файзулин Н.К., Титоян А.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Гомберг М.А., Хисматуллина З.Р., Файзулин Н.К., Титоян А.М.</copyright-holder><copyright-holder xml:lang="en">Gomberg M.A., Khismatullina Z.R., Fayzulin N.K., Titoyan A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/471">https://www.surgonco.ru/jour/article/view/471</self-uri><abstract><sec><title>Введение</title><p>Введение. Базальноклеточная карцинома является одной из наиболее часто встречаемых злокачественных опухолей кожи. Это злокачественное новообразование кожи отличается медленным ростом и низкой склонностью к метастазированию, но при агрессивном течении опухоли возможен и смертельный исход. На примере клинического случая проведен разбор ошибок при диагностике данного заболевания.</p></sec><sec><title>Описание случая</title><p>Описание случая. Пациент Б., 67 лет, обратился за медицинской помощью в Республиканский кожно-венерологический диспансер с жалобами на очаг поражения на спинке носа. Из данных анамнеза известно, что пациент изначально обратился к дерматологу по месту жительства, который назначил комбинированное наружное средство, в состав которого входил топический кортикостероид. Ввиду отсутствия динамики пациент предположил у себя наличие новообразования и самостоятельно обратился к онкологу по месту жительства. Онколог, в свою очередь, исключив свою патологию, рекомендовал наблюдение и лечение у дерматолога.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. Повторно пациент обратился за помощью только через полтора года с жалобами на увеличение очага поражения на спинке носа, появление корок черного цвета и кровоточивости. Результаты дерматоскопического исследования показали отсутствие пигментной сетки, что свидетельствовало в пользу опухолевого процесса немеланоцитарного поражения кожи. На основании данных клинического осмотра и гистологического исследования биоптата опухоли подтверждено предположение и выставлен диагноз — рак кожи носа ст. I T1N0M0 гр. III. В условиях РОД больному была проведена рентгенотерапия по радикальной программе, в режиме 5 дней в неделю на аппарате Xstrahl-300 (0545), РОД-400 сГр, СОД-4000 сГр на область опухоли кожи носа. Отмечена положительная динамика (у больного очаг поражения заэпителизировался), и в настоящее время пациент находится на диспансерном учете у онколога по месту жительства.</p></sec><sec><title>Заключение</title><p>Заключение. Отсутствие должного обследования дерматологом и онкологом по месту жительства способствовало медленному прогрессированию и росту злокачественного новообразования у пациента. Обоснована диагностическая значимость дерматоскопического метода на ранних стадиях злокачественного опухолевого процесса.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Basal cell carcinoma represents one of the most common malignant skin tumours. This malignant skin neoplasm is characterised by slow growth and a weak tendency to metastasis, although the fatal outcome with an aggressive tumour growth is also possible. On the example of a clinical case, an analysis of diagnostic errors regarding this disease was carried out.</p></sec><sec><title>Case Description</title><p>Case Description. Patient B., 67 years old, sought medical assistance in the Republican Dermatovenerologic Dispensary with complaints of a lesion on the nasal dorsum. The anamnesis indicated that the patient initially turned to a dermatologist at the place of residence, who prescribed a combined dermatic treatment containing a topical corticosteroid. Due to the lack of dynamics, the patient suggested a neoplasm and sought medical assistance from an oncologist at his place of residence. After excluding oncological pathology, the oncologist recommended observation and treatment by a dermatologist.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. Repeatedly, the patient requested medical assistance only after a year and a half with complaints of an increase in the lesion on the nasal dorsum, the appearance of black crusts and bleeding. The results of a dermatoscopic examination demonstrated the absence of a pigment network, thus confirming the tumour process of non-melanocytic skin lesion. Based on the data of the clinical examination and histological examination of the tumour biopsy, the assumption was confirmed and the diagnosis of st. I T1N0M0 gr. III nasal skin cancer, was made. Under the conditions of the Republican Dermatovenerologic Dispensary, the patient underwent X-ray therapy according to the radical program in 5 days a week by the Xstrahl-300 (0545) instrument with the single and summary tumour doses on the area of the nasal skin tumour equal to 400 and 4000 cGy, respectively. Positive dynamics was noted (the lesion focus was epithelised) and the patient is currently under the supervision of an oncologist at the place of residence.</p></sec><sec><title>Conclusions</title><p>Conclusions. The lack of proper examination by a dermatologist and oncologist at the place of residence contributed to the progression and growth of a malignant neoplasm in the patient. The diagnostic significance of the dermatoscopic method in the early stages of the malignant tumour process is substantiated.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>базальноклеточный рак</kwd><kwd>новообразования носа</kwd><kwd>новообразования кожи</kwd><kwd>ранняя диагностика</kwd><kwd>дерматоскопия</kwd><kwd>диагностические ошибки</kwd><kwd>факторы риска</kwd></kwd-group><kwd-group xml:lang="en"><kwd>basal cell cancer</kwd><kwd>nasal neoplasm</kwd><kwd>skin neoplasm</kwd><kwd>early diagnosis</kwd><kwd>dermatoscopy</kwd><kwd>diagnostic errors</kwd><kwd>risk factors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Devine C., Srinivasan B., Sayan A., Ilankovan V. Epidemiology of basal cell carcinoma: a 10-year comparative study. Br J Oral Maxillofac Surg. 2018;56(2):101-6. 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