<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2020-10-2-122-129</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-489</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Неоперативные методы лечения дивертикулита ободочной кишки (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Non-Surgical Treatment of Colonic Diverticulitis (a Review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4832-6363</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербулатов</surname><given-names>Ш. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbulatov</surname><given-names>Sh. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимербулатов Шамиль Вилевич — д.м.н., кафедра хирургии с курсом эндоскопии ИДПО.</p><p>тел.:+7(927)3073333</p></bio><bio xml:lang="en"><p>Shamil V. Timerbulatov — Dr. Sci. (Med.), Department of Surgery with a course of Endoscopy for Advanced Professional Education.</p><p>tel.: +7(927)3073333</p></bio><email xlink:type="simple">timersh@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2320-9558</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гайнуллина</surname><given-names>Э. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gainullina</surname><given-names>E. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гайнуллина Эльза Нажиповна — кафедра хирургии с курсом эндоскопии ИДПО.</p><p>тел.: +7(917)4326976</p></bio><bio xml:lang="en"><p>Elza N. Gainullina — Department of Surgery with a course of Endoscopy for Advanced Professional Education.</p><p>tel.: +7(917)4326976</p></bio><email xlink:type="simple">ehl2368@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6664-1308</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербулатов</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbulatov</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимербулатов Махмуд Вилевич — д.м.н., профессор, кафедра факультетской хирургии с курсом колопроктологии.</p><p>тел.: +7(917)3577528</p></bio><bio xml:lang="en"><p>Mahmud V. Timerbulatov — Dr. Sci. (Med.), Prof., Department of Departmental Surgery with a course of Coloproctology.</p><p>tel.: +7(917)3577528</p></bio><email xlink:type="simple">timerm@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>25</day><month>07</month><year>2020</year></pub-date><volume>10</volume><issue>2</issue><fpage>122</fpage><lpage>129</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тимербулатов Ш.В., Гайнуллина Э.Н., Тимербулатов М.В., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Тимербулатов Ш.В., Гайнуллина Э.Н., Тимербулатов М.В.</copyright-holder><copyright-holder xml:lang="en">Timerbulatov S.V., Gainullina E.N., Timerbulatov M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/489">https://www.surgonco.ru/jour/article/view/489</self-uri><abstract><p>Дивертикулярная болезнь ободочной кишки по распространенности, многообразию клинических проявлений, наличию осложнений представляет не только медицинскую, но и огромную социальную проблему. С увеличением продолжительности жизни населения до 80 лет и более она приобретает угрожающий характер. Многие принципы, использовавшиеся ранее, потеряли свою актуальность на настоящий момент. Это диктует необходимость ранней диагностики дивертикулярной болезни ободочной кишки, адекватной терапии и профилактики данной патологии. В данной статье представлен обзор литературы по консервативным методам лечения воспалительных осложнений — дивертикулита ободочной кишки. За последние 20 лет отмечен заметный рост числа госпитализаций пациентов с осложненным дивертикулитом (до 20 %), что также увеличивает финансовые расходы на лечение. Рассмотрены вопросы диагностики, критерии оценки тяжести дивертикулита на основании лабораторных, биохимических исследований, лучевых методов визуализации (компьютерная томография, магнитно-резонансная томография, ультразвуковое исследование, колоноскопия). Проведен критический анализ возможностей противовоспалительных, антибактериальных препаратов в профилактике рецидивов и лечении острого и рецидивного дивертикулита, показания к амбулаторному ведению. Несмотря на множество проведенных клинических исследований и опубликованных рекомендаций, вопросы выбора лекарственных препаратов, их дозировок и длительности приема остаются открытыми.</p></abstract><trans-abstract xml:lang="en"><p>Colonic diverticulitis poses an adverse medical and social problem for its prevalence, variety of clinical manifestations and complications and is becoming menacing as the people’s life expectancy reaches beyond 80 years. Many of the traditional principles no longer apply. This situation warrants an earlier diagnosis of colonic diverticulitis, its adequate treatment and prevention. The article presents a review of current literature on the conservative treatment of inflammatory colonic diverticulitis. The past 20 years have witnessed a noticeable increase to 20 % of hospitalisation rate with complicated diverticulitis and a higher associated financial burden. We discuss issues in the diagnosis and criteria for diverticulitis severity assessment with laboratory, biochemical data and radiation imaging (computer tomography, magnetic resonance imaging, ultrasound, colonoscopy). A critical overview is provided on anti-inflammatory and antibiotic drug usage in recurrence prevention and treatment of acute and recurrent diverticulitis, aside to recommendations in outpatient care. Despite a manifold of clinical studies and guidelines available, the adequate choice of drugs, dosages and duration of treatment remains an open challenge.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дивертикулит ободочной кишки</kwd><kwd>заболеваемость</kwd><kwd>дифференциальная диагностика</kwd><kwd>С-реактивный белок</kwd><kwd>прокальцитонин</kwd><kwd>компьютерная диагностика</kwd><kwd>антибиотики</kwd><kwd>факторы риска</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colonic diverticulitis</kwd><kwd>morbidity</kwd><kwd>diff erential diagnostics</kwd><kwd>C-reactive protein</kwd><kwd>procalcitonin</kwd><kwd>computer diagnostics</kwd><kwd>antibiotics</kwd><kwd>risk factors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rezapour M., Ali S., Stollman N. Diverticular disease: an update on pathogenesis and management. Gut Liver. 2018;12:125–32. DOI: 10.5009/gnl16552</mixed-citation><mixed-citation xml:lang="en">Rezapour M., Ali S., Stollman N. Diverticular disease: an update on pathogenesis and management. Gut Liver. 2018;12:125–32. DOI: 10.5009/gnl16552</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Peery AF. Recent Advances in Diverticular Disease. Curr Gastroenterol Rep. 2016 Jul;18(7):37. DOI: 10.1007/s11894-016-0513-1</mixed-citation><mixed-citation xml:lang="en">Peery AF. Recent Advances in Diverticular Disease. Curr Gastroenterol Rep. 2016 Jul;18(7):37. DOI: 10.1007/s11894-016-0513-1</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kupcinskas J., Strate L.L., Bassotti G., Torti G., Herszènyi L., Malfertheiner P., et al. Pathogenesis of diverticulosis and diverticular disease. J Gastrointestin Liver Dis. 2019;28(suppl. 4):7–10. DOI: 10.15403/jgld-551</mixed-citation><mixed-citation xml:lang="en">Kupcinskas J., Strate L.L., Bassotti G., Torti G., Herszènyi L., Malfertheiner P., et al. Pathogenesis of diverticulosis and diverticular disease. J Gastrointestin Liver Dis. 2019;28(suppl. 4):7–10. DOI: 10.15403/jgld-551</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Peery A.F., Crockett S.D., Murphy C.C., Lund J.L., Dellon E.S., Williams J.L., et al. Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: Update 2018. Gastroenterology. 2019;156:254–72.e11. DOI: 10.1053/j.gastro.2018.08.063</mixed-citation><mixed-citation xml:lang="en">Peery A.F., Crockett S.D., Murphy C.C., Lund J.L., Dellon E.S., Williams J.L., et al. Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: Update 2018. Gastroenterology. 2019;156:254–72.e11. DOI: 10.1053/j.gastro.2018.08.063</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Wheat C.L., Strate L.L. Trends in hospitalization for diverticulitis and diverticular bleeding in the United States from 2000 to 2010. Clin Gastroenterol Hepatol. 2016;14:96–103.e1. DOI: 10.1016/j.cgh.2015.03.030</mixed-citation><mixed-citation xml:lang="en">Wheat C.L., Strate L.L. Trends in hospitalization for diverticulitis and diverticular bleeding in the United States from 2000 to 2010. Clin Gastroenterol Hepatol. 2016;14:96–103.e1. DOI: 10.1016/j.cgh.2015.03.030</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Peery A.F., Crockett S.D., Barritt A.S., Dellon E.S., Eluri S., Gangarosa L.M., et al. Burden of gastrointestinal, liver, and pancreatic diseases in the United States. Gastroenterology. 2015;149:1731–41.e3. DOI: 10.1053/j.gastro.2015.08.045</mixed-citation><mixed-citation xml:lang="en">Peery A.F., Crockett S.D., Barritt A.S., Dellon E.S., Eluri S., Gangarosa L.M., et al. Burden of gastrointestinal, liver, and pancreatic diseases in the United States. Gastroenterology. 2015;149:1731–41.e3. DOI: 10.1053/j.gastro.2015.08.045</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bollom A., Austrie J., Hirsch W., Nee j., Friedlander D., Ellingson K., et al. Emergency department burden of diverticulitis in the USA, 2006–2013. Dig Dis Sci. 2017;62:2694–703. DOI: 10.1007/s10620-017-4525-y</mixed-citation><mixed-citation xml:lang="en">Bollom A., Austrie J., Hirsch W., Nee j., Friedlander D., Ellingson K., et al. Emergency department burden of diverticulitis in the USA, 2006–2013. Dig Dis Sci. 2017;62:2694–703. DOI: 10.1007/s10620-017-4525-y</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Masoomi H., Buchberg B., Nguyen B., Tung V., Stamos M.J., Mills S. Outcomes of laparoscopic versus open colectomy in elective surgery for diverticulitis. World J Surg. 2011;35:2143–8. DOI: 10.1007/s00268-011-1117-4</mixed-citation><mixed-citation xml:lang="en">Masoomi H., Buchberg B., Nguyen B., Tung V., Stamos M.J., Mills S. Outcomes of laparoscopic versus open colectomy in elective surgery for diverticulitis. World J Surg. 2011;35:2143–8. DOI: 10.1007/s00268-011-1117-4</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Jeger V., Pop R., Forudastan F., Barras J.P., Zuber M., Piso R.J. Is there a role for procalcitonin in diff erentiating uncomplicated and complicated diverticulitis in order to reduce antibiotic therapy? A prospective diagnostic cohort study. Swiss Med Wkly. 2017;147:w14555. DOI: 10.4414/smw.2017.14555</mixed-citation><mixed-citation xml:lang="en">Jeger V., Pop R., Forudastan F., Barras J.P., Zuber M., Piso R.J. Is there a role for procalcitonin in diff erentiating uncomplicated and complicated diverticulitis in order to reduce antibiotic therapy? A prospective diagnostic cohort study. Swiss Med Wkly. 2017;147:w14555. DOI: 10.4414/smw.2017.14555</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hogan J., Sehgal R., Murphy D., O’Leary P., Coff ey J.C. Do infl ammatory indices play a role in distinguishing between uncomplicated and complicated diverticulitis? Dig Surg.2017;34:7–11. DOI: 10.1159/000447250</mixed-citation><mixed-citation xml:lang="en">Hogan J., Sehgal R., Murphy D., O’Leary P., Coff ey J.C. Do infl ammatory indices play a role in distinguishing between uncomplicated and complicated diverticulitis? Dig Surg.2017;34:7–11. DOI: 10.1159/000447250</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kechagias A., Rautio T., Makela J. Th e early c-reactive protein trend does not have a role in monitoring acute diverticulitis progression. Chirurgia (Bucur). 2016;111(1):43–7. PMID: 26988538</mixed-citation><mixed-citation xml:lang="en">Kechagias A., Rautio T., Makela J. Th e early c-reactive protein trend does not have a role in monitoring acute diverticulitis progression. Chirurgia (Bucur). 2016;111(1):43–7. PMID: 26988538</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Mäkelä J.T., Klintrup K., Takala H., Rautio T. Th e role of C-reactive protein in prediction of the severity of acute diverticulitis in an emergency unit. Scand J Gastroenterol. 2015;50(5):536–41. DOI: 10.3109/00365521.2014.999350</mixed-citation><mixed-citation xml:lang="en">Mäkelä J.T., Klintrup K., Takala H., Rautio T. Th e role of C-reactive protein in prediction of the severity of acute diverticulitis in an emergency unit. Scand J Gastroenterol. 2015;50(5):536–41. DOI: 10.3109/00365521.2014.999350</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Bolkenstein H.E., van de Wall B.J., Consten E.C., van der Palen J., Broeders I.A, Draaisma W.A. Development and validation of a diagnostic prediction model distinguishing complicated from uncomplicated diverticulitis. Scand J Gastroenterol. 2018;53(10-11):1291–7. DOI: 10.1080/00365521.2018.1517188</mixed-citation><mixed-citation xml:lang="en">Bolkenstein H.E., van de Wall B.J., Consten E.C., van der Palen J., Broeders I.A, Draaisma W.A. Development and validation of a diagnostic prediction model distinguishing complicated from uncomplicated diverticulitis. Scand J Gastroenterol. 2018;53(10-11):1291–7. DOI: 10.1080/00365521.2018.1517188</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Alshamari M., Norrman E., Geijer M., Jansson K., Geijer H. Diagnostic accuracy of low-dose CT compared with abdominal radiography in non-traumatic acute abdominal pain: prospective study and systematic review. Eur Radiol. 2016;26:1766–74. DOI: 10.1007/s00330-015-3984-9</mixed-citation><mixed-citation xml:lang="en">Alshamari M., Norrman E., Geijer M., Jansson K., Geijer H. Diagnostic accuracy of low-dose CT compared with abdominal radiography in non-traumatic acute abdominal pain: prospective study and systematic review. Eur Radiol. 2016;26:1766–74. DOI: 10.1007/s00330-015-3984-9</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Wasvary H., Turfah F., Kadro O., Beauregard W. Same hospitalization resection for acute diverticulitis. Am Surg. 1999;65:632–6. PMID: 10399971</mixed-citation><mixed-citation xml:lang="en">Wasvary H., Turfah F., Kadro O., Beauregard W. Same hospitalization resection for acute diverticulitis. Am Surg. 1999;65:632–6. PMID: 10399971</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Hall J.F., Roberts P.L., Ricciardi R., Read T., Scheirey C., Wald C, et al. Long-term follow-up aft er an initial episode of diverticulitis: what are the predictors of recurrence? Dis Colon Rectum. 2011;54(3):283–8. DOI: 10.1007/DCR.0b013e3182028576</mixed-citation><mixed-citation xml:lang="en">Hall J.F., Roberts P.L., Ricciardi R., Read T., Scheirey C., Wald C, et al. Long-term follow-up aft er an initial episode of diverticulitis: what are the predictors of recurrence? Dis Colon Rectum. 2011;54(3):283–8. DOI: 10.1007/DCR.0b013e3182028576</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kameda T., Kawai F., Taniguchi N., Kobori Y. Usefulness of transabdominal ultrasonography in excluding adnexal disease. J Med Ultrason (2001). 2016;43(1):63–70. DOI: 10.1007/s10396-015-0666-9</mixed-citation><mixed-citation xml:lang="en">Kameda T., Kawai F., Taniguchi N., Kobori Y. Usefulness of transabdominal ultrasonography in excluding adnexal disease. J Med Ultrason (2001). 2016;43(1):63–70. DOI: 10.1007/s10396-015-0666-9</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Nielsen K., Richir M.C., Stolk T.T., van der Ploeg T., Moormann G.R.H.M., Wiarda B.M., et al. Th e limited role of ultrasound in the diagnostic process of colonic diverticulitis. World J Surg. 2014;38(7):1814–8. DOI: 10.1007/s00268-013-2423-9</mixed-citation><mixed-citation xml:lang="en">Nielsen K., Richir M.C., Stolk T.T., van der Ploeg T., Moormann G.R.H.M., Wiarda B.M., et al. Th e limited role of ultrasound in the diagnostic process of colonic diverticulitis. World J Surg. 2014;38(7):1814–8. DOI: 10.1007/s00268-013-2423-9</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Schreyer A.G., Layer G., German Society of Digestive and Metabolic Diseases (DGVS) as well as the German Society of General and Visceral Surgery (DGAV) in collaboration with the German Radiology Society (DRG). S2k guidlines for diverticular disease and diverticulitis: diagnosis, classifi cation, and therapy for the radiologist. Rofo. 2015;187(8):676–84. DOI: 10.1055/s-0034-1399526</mixed-citation><mixed-citation xml:lang="en">Schreyer A.G., Layer G., German Society of Digestive and Metabolic Diseases (DGVS) as well as the German Society of General and Visceral Surgery (DGAV) in collaboration with the German Radiology Society (DRG). S2k guidlines for diverticular disease and diverticulitis: diagnosis, classifi cation, and therapy for the radiologist. Rofo. 2015;187(8):676–84. DOI: 10.1055/s-0034-1399526</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Dirks K., Calabrese E., Dietrich C.F., Gilja O.H., Hausken T., Higginson A., et al. EFSUMB position paper: recommendations for gastrointestinal ultrasound (GIUS) in acute appendicitis and diverticulitis. Ultraschall Med. 2019;40(2):163–75. DOI: 10.1055/a-0824-6952</mixed-citation><mixed-citation xml:lang="en">Dirks K., Calabrese E., Dietrich C.F., Gilja O.H., Hausken T., Higginson A., et al. EFSUMB position paper: recommendations for gastrointestinal ultrasound (GIUS) in acute appendicitis and diverticulitis. Ultraschall Med. 2019;40(2):163–75. DOI: 10.1055/a-0824-6952</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">istä E., Hjern F., Blomqvist L., Von Heijne A., Abraham-Nordling M. Cancer and diverticulitis of the sigmoid colon. Diff erentiation with computed tomography versus magneticresonance imaging: preliminary experiences. Acta Radiol. 2013;54(3):237–41. DOI: 10.1258/ar.2012.120543</mixed-citation><mixed-citation xml:lang="en">istä  E., Hjern F., Blomqvist L., Von Heijne A., Abraham-Nordling M. Cancer and diverticulitis of the sigmoid colon. Diff erentiation with computed tomography versus magneticresonance imaging: preliminary experiences. Acta Radiol. 2013;54(3):237–41. DOI: 10.1258/ar.2012.120543</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Daniels L., Unlu C., de Korte N., van Dieren S., Stockmann H.B., Vrouenraets B.C., et al. Randomized clinical trial of observational versus antibiotic treatment for a fi rst episode of CT-proven uncomplicated acute diverticulitis. Br J Surg. 2017;104(1):52–61. DOI: 10.1002/bjs.10309</mixed-citation><mixed-citation xml:lang="en">Daniels L., Unlu C., de Korte N., van Dieren S., Stockmann H.B., Vrouenraets B.C., et al. Randomized clinical trial of observational versus antibiotic treatment for a fi rst episode of CT-proven uncomplicated acute diverticulitis. Br J Surg. 2017;104(1):52–61. DOI: 10.1002/bjs.10309</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Mege D., Yeo H. Meta-analyses of current strategies to treat uncomplicated diverticulitis. Dis Colon Rectum. 2019;62(3):371–8. DOI: 10.1097/DCR.0000000000001295</mixed-citation><mixed-citation xml:lang="en">Mege D., Yeo H. Meta-analyses of current strategies to treat uncomplicated diverticulitis. Dis Colon Rectum. 2019;62(3):371–8. DOI: 10.1097/DCR.0000000000001295</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Isacson D., Smedh K., Nikberg M., Chabok A. Long-term follow-up of the AVOD randomized trial of antibiotic avoidance in uncomplicated diverticulitis. Br J Surg. 2019;106(11):1542–8. DOI: 10.1002/bjs.11239</mixed-citation><mixed-citation xml:lang="en">Isacson D., Smedh K., Nikberg M., Chabok A. Long-term follow-up of the AVOD randomized trial of antibiotic avoidance in uncomplicated diverticulitis. Br J Surg. 2019;106(11):1542–8. DOI: 10.1002/bjs.11239</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">van Dijk S.T., Daniels L., Unlu C., de Korte N., van Dieren S., Stockmann H.B., et al. Long-term eff ects of omitting antibiotics in uncomplicated acute diverticulitis. Am J Gastroenterol. 2018;113(7):1045–52. DOI: 10.1038/s41395-018-0030-y</mixed-citation><mixed-citation xml:lang="en">van Dijk S.T., Daniels L., Unlu C., de Korte N., van Dieren S., Stockmann H.B., et al. Long-term eff ects of omitting antibiotics in uncomplicated acute diverticulitis. Am J Gastroenterol. 2018;113(7):1045–52. DOI: 10.1038/s41395-018-0030-y</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Shabanzadeh D.M., Wille-Jørgensen P. Antibiotics for uncomplicated diverticulitis. Cochrane Database System Rev. 2012;(11):CD009092. DOI: 10.1002/14651858.CD009092.pub2.</mixed-citation><mixed-citation xml:lang="en">Shabanzadeh D.M., Wille-Jørgensen P. Antibiotics for uncomplicated diverticulitis. Cochrane Database System Rev. 2012;(11):CD009092. DOI: 10.1002/14651858.CD009092.pub2.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Estrada Ferrer O., Ruiz Edo N., Hidalgo Grau L.A., Abadal Prades M., Del Bas Rubia M., Garcia Torralbo E.M., et al. Selective nonantibiotic treatment in sigmoid diverticulitis: is it time to change the traditional approach? Tech Coloproctol. 2016;20(5):309–15. DOI: 10.1007/s10151-016-1464-0</mixed-citation><mixed-citation xml:lang="en">Estrada Ferrer O., Ruiz Edo N., Hidalgo Grau L.A., Abadal Prades M., Del Bas Rubia M., Garcia Torralbo E.M., et al. Selective nonantibiotic treatment in sigmoid diverticulitis: is it time to change the traditional approach? Tech Coloproctol. 2016;20(5):309–15. DOI: 10.1007/s10151-016-1464-0</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Emile S.H., Elfeki H., Sakr A., Shalaby M. Management of acute uncomplicated diverticulitis without antibiotics: a systematic review, meta-analysis, and meta-regression of predictors of treatment failure. Tech Coloproctol. 2018;22(7):499–509. DOI: 10.1007/s10151-018-1817-y</mixed-citation><mixed-citation xml:lang="en">Emile S.H., Elfeki H., Sakr A., Shalaby M. Management of acute uncomplicated diverticulitis without antibiotics: a systematic review, meta-analysis, and meta-regression of predictors of treatment failure. Tech Coloproctol. 2018;22(7):499–509. DOI: 10.1007/s10151-018-1817-y</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Bolkenstein H.E., Draaisma W.A., van de Wall B., Consten E., Broeders I. Treatment of acute uncomplicated diverticulitis without antibiotics: risk factors for treatment failure. Int J ColorectalDis. 2018;33(7):863–9. DOI: 10.1007/s00384-018-3055-1</mixed-citation><mixed-citation xml:lang="en">Bolkenstein H.E., Draaisma W.A., van de Wall B., Consten E., Broeders I. Treatment of acute uncomplicated diverticulitis without antibiotics: risk factors for treatment failure. Int J ColorectalDis. 2018;33(7):863–9. DOI: 10.1007/s00384-018-3055-1</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Feingold D., Steele S.R., Lee S., Kaiser A., Boushey R., Buie W.D., et al. Practice parameters for the treatment of sigmoid diverticulitis. Dis Colon Rectum. 2014;57(3):284–94. DOI: 10.1097/DCR.0000000000000075</mixed-citation><mixed-citation xml:lang="en">Feingold D., Steele S.R., Lee S., Kaiser A., Boushey R., Buie W.D., et al. Practice parameters for the treatment of sigmoid diverticulitis. Dis Colon Rectum. 2014;57(3):284–94. DOI: 10.1097/DCR.0000000000000075</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Schug-Pass C., Geers P., Hugel O., Lippert H., Kockerling F. Prospective randomized trial comparing short-term antibiotic therapy versus standard therapy for acute uncomplicated sigmoid diverticulitis. Int J Colorectal Dis. 2010;25(6):751–9. DOI: 10.1007/s00384-010-0899-4</mixed-citation><mixed-citation xml:lang="en">Schug-Pass C., Geers P., Hugel O., Lippert H., Kockerling F. Prospective randomized trial comparing short-term antibiotic therapy versus standard therapy for acute uncomplicated sigmoid diverticulitis. Int J Colorectal Dis. 2010;25(6):751–9. DOI: 10.1007/s00384-010-0899-4</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Biondo S., Golda T., Kreisler E., Espin E., Vallribera F., Oteiza F., et al. Outpatient versus hospitalization management for uncomplicated diverticulitis: a prospective, multicenter randomized clinical trial (DIVER Trial). Ann Surg. 2014;259(1):38–44. DOI: 10.1097/SLA.0b013e3182965a11</mixed-citation><mixed-citation xml:lang="en">Biondo S., Golda T., Kreisler E., Espin E., Vallribera F., Oteiza F., et al. Outpatient versus hospitalization management for uncomplicated diverticulitis: a prospective, multicenter randomized clinical trial (DIVER Trial). Ann Surg. 2014;259(1):38–44. DOI: 10.1097/SLA.0b013e3182965a11</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Gregersen R., Mortensen L.Q., Burcharth J., Pommergaard H.C., Rosenberg J. Treatment of patients with acute colonic diverticulitis complicated by abscess formation: a systematic review. Int J Surg. 2016;35:201–8. DOI: 10.1016/j.ijsu.2016.10.006</mixed-citation><mixed-citation xml:lang="en">Gregersen R., Mortensen L.Q., Burcharth J., Pommergaard H.C., Rosenberg J. Treatment of patients with acute colonic diverticulitis complicated by abscess formation: a systematic review. Int J Surg. 2016;35:201–8. DOI: 10.1016/j.ijsu.2016.10.006</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Elagili F., Stocchi L., Ozuner G., Kiran R.P. Antibiotics alone instead of percutaneous drainage as initial treatment of large diverticular abscess. Tech Coloproctol. 2015;19(2):97–103. DOI: 10.1007/s10151-014-1250-9</mixed-citation><mixed-citation xml:lang="en">Elagili F., Stocchi L., Ozuner G., Kiran R.P. Antibiotics alone instead of percutaneous drainage as initial treatment of large diverticular abscess. Tech Coloproctol. 2015;19(2):97–103. DOI: 10.1007/s10151-014-1250-9</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Devaraj B., Liu W., Tatum J., Cologne K., Kaiser A.M. Medically treated diverticular abscess associated with high risk of recurrence and disease complications. Dis Colon Rectum. 2016;59(3):208–15. DOI: 10.1097/DCR.0000000000000533</mixed-citation><mixed-citation xml:lang="en">Devaraj B., Liu W., Tatum J., Cologne K., Kaiser A.M. Medically treated diverticular abscess associated with high risk of recurrence and disease complications. Dis Colon Rectum. 2016;59(3):208–15. DOI: 10.1097/DCR.0000000000000533</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Garfi nkle R., Kugler A., Pelsser V., Vasilevsky C.-A., Morin N., Gordon P., et al. Diverticular abscess managed with long-term defi nitive nonoperative intent is safe. Dis Colon Rectum. 2016;59(7):648–55. DOI: 10.1097/DCR.0000000000000624</mixed-citation><mixed-citation xml:lang="en">Garfi nkle R., Kugler A., Pelsser V., Vasilevsky C.-A., Morin N., Gordon P., et al. Diverticular abscess managed with long-term defi nitive nonoperative intent is safe. Dis Colon Rectum. 2016;59(7):648–55. DOI: 10.1097/DCR.0000000000000624</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Toorenvliet B.R., Swank H., Schoones J.W., Hamming J.F., Bemelman W.A. Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Colorectal Dis. 2010;12(9):862–7. DOI: 10.1111/j.1463-1318.2009.02052.x</mixed-citation><mixed-citation xml:lang="en">Toorenvliet B.R., Swank H., Schoones J.W., Hamming J.F., Bemelman W.A. Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Colorectal Dis. 2010;12(9):862–7. DOI: 10.1111/j.1463-1318.2009.02052.x</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Strate L.L., Morris A.M. Epidemiology, pathophysiology, and treatment of diverticulitis. Gastroenterology. 2019;156(5):1282–98.e1. DOI: 10.1053/j.gastro.2018.12.033</mixed-citation><mixed-citation xml:lang="en">Strate L.L., Morris A.M. Epidemiology, pathophysiology, and treatment of diverticulitis. Gastroenterology. 2019;156(5):1282–98.e1. DOI: 10.1053/j.gastro.2018.12.033</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Schafmayer C., Harrison J.W., Buch S., Lange Ch., Reichert M.C., Hofer Ph., et al. Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms. Gut. 2019;68(5):854–65. DOI: 10.1136/gutjnl-2018-317619</mixed-citation><mixed-citation xml:lang="en">Schafmayer C., Harrison J.W., Buch S., Lange Ch., Reichert M.C., Hofer Ph., et al. Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms. Gut. 2019;68(5):854–65. DOI: 10.1136/gutjnl-2018-317619</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Strate L.L., Keeley B.R., Cao Y., Wu K., Giovannucci E.L., Chan AT. Western dietary pattern increases, and prudent dietary pattern decreases, risk of incident diverticulitis in a prospective cohort study. Gastroenterology. 2017;152(5):1023–30.e2. DOI: 10.1053/j.gastro.2016.12.038</mixed-citation><mixed-citation xml:lang="en">Strate L.L., Keeley B.R., Cao Y., Wu K., Giovannucci E.L., Chan AT. Western dietary pattern increases, and prudent dietary pattern decreases, risk of incident diverticulitis in a prospective cohort study. Gastroenterology. 2017;152(5):1023–30.e2. DOI: 10.1053/j.gastro.2016.12.038</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Liu P.H., Cao Y., Keeley B.R., Tam I., Wu K., Strate L.L., et al. Adherence to a healthy lifestyle is associated with a lower risk of diverticulitis among men. Am J Gastroenterol. 2017;112(12):1868–76. DOI: 10.1038/ajg.2017.398</mixed-citation><mixed-citation xml:lang="en">Liu P.H., Cao Y., Keeley B.R., Tam I., Wu K., Strate L.L., et al. Adherence to a healthy lifestyle is associated with a lower risk of diverticulitis among men. Am J Gastroenterol. 2017;112(12):1868–76. DOI: 10.1038/ajg.2017.398</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Aune D., Sen A., Norat T., Riboli E. Dietary fi bre intake and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies. Eur J Nutr. 2020;59(2):421–32. DOI: 10.1007/s00394-019-01967-w</mixed-citation><mixed-citation xml:lang="en">Aune D., Sen A., Norat T., Riboli E. Dietary fi bre intake and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies. Eur J Nutr. 2020;59(2):421–32. DOI: 10.1007/s00394-019-01967-w</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Aune D., Sen A., Leitzmann M.F., Tonstad S., Norat T., Vatten LJ. Tobacco smoking and the risk of diverticular disease — a systematic review and meta-analysis of prospective studies. Colorectal Dis. 2017;19(7):621–33. DOI: 10.1111/codi.13748</mixed-citation><mixed-citation xml:lang="en">Aune D., Sen A., Leitzmann M.F., Tonstad S., Norat T., Vatten LJ. Tobacco smoking and the risk of diverticular disease — a systematic review and meta-analysis of prospective studies. Colorectal Dis. 2017;19(7):621–33. DOI: 10.1111/codi.13748</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Aune D., Sen A., Leitzmann M.F., Norat T., Tonstad S., Vatten L.J. Body mass index and physical activity and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies. Eur J Nutr. 2017;56(8):2423–38. DOI: 10.1007/s00394-017-1443-x</mixed-citation><mixed-citation xml:lang="en">Aune D., Sen A., Leitzmann M.F., Norat T., Tonstad S., Vatten L.J. Body mass index and physical activity and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies. Eur J Nutr. 2017;56(8):2423–38. DOI: 10.1007/s00394-017-1443-x</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Picchio M., Elisei W., Brandimarte G., Di Mario F., Malfertheiner P., Scarpignato C., et al. Mesalazine for the treatment of symptomatic uncomplicated diverticular disease of the colon and for primary prevention of diverticulitis: a systematic review of randomized clinical trials. J Clin Gastroenterol. 2016;50(suppl 1):S64–9. DOI: 10.1097/MCG.0000000000000669</mixed-citation><mixed-citation xml:lang="en">Picchio M., Elisei W., Brandimarte G., Di Mario F., Malfertheiner P., Scarpignato C., et al. Mesalazine for the treatment of symptomatic uncomplicated diverticular disease of the colon and for primary prevention of diverticulitis: a systematic review of randomized clinical trials. J Clin Gastroenterol. 2016;50(suppl 1):S64–9. DOI: 10.1097/MCG.0000000000000669</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Picchio M., Elisei W., Tursi A. Mesalazine to treat symptomatic uncomplicated diverticular disease and to prevent acute diverticulitis occurrence. A systematic review with meta-analysis of randomized, placebo-controlled trials. J Gastrointestin Liver Dis. 2018;27(3):291–7. DOI: 10.15403/jgld.2014.1121.273.pic</mixed-citation><mixed-citation xml:lang="en">Picchio M., Elisei W., Tursi A. Mesalazine to treat symptomatic uncomplicated diverticular disease and to prevent acute diverticulitis occurrence. A systematic review with meta-analysis of randomized, placebo-controlled trials. J Gastrointestin Liver Dis. 2018;27(3):291–7. DOI: 10.15403/jgld.2014.1121.273.pic</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Carter F., Alsayb M., Marshall J.K., Yuan Y. Mesalamine (5-ASA) for the prevention of recurrent diverticulitis. Cochrane Database Syst Rev. 2017;10:CD009839. DOI: 10.1002/14651858.CD009839.pub2</mixed-citation><mixed-citation xml:lang="en">Carter F., Alsayb M., Marshall J.K., Yuan Y. Mesalamine (5-ASA) for the prevention of recurrent diverticulitis. Cochrane Database Syst Rev. 2017;10:CD009839. DOI: 10.1002/14651858.CD009839.pub2</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Lanas A., Ponce J., Bignamini A., Mearin F. One year intermittent rifaximin plus fi bre supplementation vs. fi bre supplementation alone to prevent diverticulitis recurrence: a proof-of-concept study. Dig Liver Dis. 2013;45(2):104–9. DOI: 10.1016/j.dld.2012.09.006</mixed-citation><mixed-citation xml:lang="en">Lanas A., Ponce J., Bignamini A., Mearin F. One year intermittent rifaximin plus fi bre supplementation vs. fi bre supplementation alone to prevent diverticulitis recurrence: a proof-of-concept study. Dig Liver Dis. 2013;45(2):104–9. DOI: 10.1016/j.dld.2012.09.006</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Moniuszko A., Rydzewska G. Th e eff ect of cyclic rifaximin therapy on symptoms of diverticular disease from the perspective of the gastroenterology outpatient clinic: a “real-life” study. Prz Gastroenterol. 2017;12(2):145–51. DOI: 10.5114/pg.2017.68167</mixed-citation><mixed-citation xml:lang="en">Moniuszko A., Rydzewska G. Th e eff ect of cyclic rifaximin therapy on symptoms of diverticular disease from the perspective of the gastroenterology outpatient clinic: a “real-life” study. Prz Gastroenterol. 2017;12(2):145–51. DOI: 10.5114/pg.2017.68167</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Bianchi M., Festa V., Moretti A., Ciaco A., Mangone M., Tornatore V., et al. Meta-analysis: long-term therapy with rifaximin in the management of uncomplicated diverticular disease. Aliment Pharmacol Th er. 2011;33(8):902–10. DOI: 10.1111/j.1365-2036.2011.04606.x</mixed-citation><mixed-citation xml:lang="en">Bianchi M., Festa V., Moretti A., Ciaco A., Mangone M., Tornatore V., et al. Meta-analysis: long-term therapy with rifaximin in the management of uncomplicated diverticular disease. Aliment Pharmacol Th er. 2011;33(8):902–10. DOI: 10.1111/j.1365-2036.2011.04606.x</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Tursi A., Brandimarte G., Elisei W., Picchio M., Forti G., Pianese G., et al. Randomised clinical trial: mesalazine and/or probiotics in maintaining remission of symptomatic uncomplicated diverticular disease–a double- blind, randomised, placebo-controlled study. Aliment Pharmacol Th er. 2013;38(7):741–51. DOI: 10.1111/apt.12463</mixed-citation><mixed-citation xml:lang="en">Tursi A., Brandimarte G., Elisei W., Picchio M., Forti G., Pianese G., et al. Randomised clinical trial: mesalazine and/or probiotics in maintaining remission of symptomatic uncomplicated diverticular disease–a double- blind, randomised, placebo-controlled study. Aliment Pharmacol Th er. 2013;38(7):741–51. DOI: 10.1111/apt.12463</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Suhardja T.S., Norhadi S., Seah E.Z., Rodgers-Wilson S. Is early colonoscopy aft er CT-diagnosed diverticulitis still necessary? Int J Colorectal Dis. 2017;32(4):485–9. DOI: 10.1007/s00384-016-2749-5</mixed-citation><mixed-citation xml:lang="en">Suhardja T.S., Norhadi S., Seah E.Z., Rodgers-Wilson S. Is early colonoscopy aft er CT-diagnosed diverticulitis still necessary? Int J Colorectal Dis. 2017;32(4):485–9. DOI: 10.1007/s00384-016-2749-5</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Sallinen V., Mentula P., Leppдniemi A. Risk of colon cancer aft er computed tomography-diagnosed acute diverticulitis: is routine colonoscopy necessary? Surg Endosc. 2014;28(3):961–6. DOI: 10.1007/s00464-013-3257-0</mixed-citation><mixed-citation xml:lang="en">Sallinen V., Mentula P., Leppдniemi A. Risk of colon cancer aft er computed tomography-diagnosed acute diverticulitis: is routine colonoscopy necessary? Surg Endosc. 2014;28(3):961–6. DOI: 10.1007/s00464-013-3257-0</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Sharma P.V., Eglinton T., Hider P., Frizelle F. Systematic review and meta-analysis of the role of routine colonic evaluation aft er radiologically confi rmed acute diverticulitis. Ann Surg. 2014;259(2):263–72. DOI: 10.1097/SLA.0000000000000294</mixed-citation><mixed-citation xml:lang="en">Sharma P.V., Eglinton T., Hider P., Frizelle F. Systematic review and meta-analysis of the role of routine colonic evaluation aft er radiologically confi rmed acute diverticulitis. Ann Surg. 2014;259(2):263–72. DOI: 10.1097/SLA.0000000000000294</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Meyer J., Orci L.A., Combescure C., et al. Risk of colorectal cancer in patients with acute diverticulitis: a systematic review and metaanalysis of observational studies. Clin Gastroenterol Hepatol. 2019;17(8):1448–56.e17. DOI: 10.1016/j.cgh.2018.07.031</mixed-citation><mixed-citation xml:lang="en">Meyer J., Orci L.A., Combescure C., et al. Risk of colorectal cancer in patients with acute diverticulitis: a systematic review and metaanalysis of observational studies. Clin Gastroenterol Hepatol. 2019;17(8):1448–56.e17. DOI: 10.1016/j.cgh.2018.07.031</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Lahat A., Yanai H., Menachem Y., Avidan B., Bar-Meir S. Th e feasibility and risk of early colonoscopy in acute diverticulitis: a prospective controlled study. Endoscopy. 2007;39(6):521–4. DOI: 10.1055/s-2007-966399</mixed-citation><mixed-citation xml:lang="en">Lahat A., Yanai H., Menachem Y., Avidan B., Bar-Meir S. Th e feasibility and risk of early colonoscopy in acute diverticulitis: a prospective controlled study. Endoscopy. 2007;39(6):521–4. DOI: 10.1055/s-2007-966399</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Elmi A., Hedgire S.S., Pargaonkar V., Cao K., McDermott S., Harisinghani M. Is early colonoscopy benefi cial in patients with CT-diagnosed diverticulitis? AJR Am J Roentgenol. 2013;200(6):1269–74. DOI: 10.2214/AJR.12.9539</mixed-citation><mixed-citation xml:lang="en">Elmi A., Hedgire S.S., Pargaonkar V., Cao K., McDermott S., Harisinghani M. Is early colonoscopy benefi cial in patients with CT-diagnosed diverticulitis? AJR Am J Roentgenol. 2013;200(6):1269–74. DOI: 10.2214/AJR.12.9539</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Ramphal W., Schreinemakers J.M., Seerden T.C., Crolla R.M., Rijken A.M., Gobardhan P.D. What is the risk of colorectal cancer aft er an episode of acute diverticulitis in conservatively treated patients? J Clin Gastroenterol. 2016;50(4):e35–9. DOI: 10.1097/MCG.0000000000000373</mixed-citation><mixed-citation xml:lang="en">Ramphal W., Schreinemakers J.M., Seerden T.C., Crolla R.M., Rijken A.M., Gobardhan P.D. What is the risk of colorectal cancer aft er an episode of acute diverticulitis in conservatively treated patients? J Clin Gastroenterol. 2016;50(4):e35–9. DOI: 10.1097/MCG.0000000000000373</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Walker A.S., Bingham J.R., Janssen K.M., et al. Colonoscopy aft er Hinchey I and II left -sided diverticulitis: utility or futility? Am J Surg. 2016;212(5):837–43. DOI: 10.1016/j.amjsurg.2016.02.012</mixed-citation><mixed-citation xml:lang="en">Walker A.S., Bingham J.R., Janssen K.M., et al. Colonoscopy aft er Hinchey I and II left -sided diverticulitis: utility or futility? Am J Surg. 2016;212(5):837–43. DOI: 10.1016/j.amjsurg.2016.02.012</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
