surgoncoКреативная хирургия и онкологияCreative surgery and oncology2076-30932307-0501Башкирский государственный медицинский университет10.24060/2076-3093-2021-11-2-174-182surgonco-588Research ArticleОБЗОР ЛИТЕРАТУРЫREVIEWSНейроэндокринные опухоли. Обзор литературыNeuroendocrine Tumours: a Literature Reviewhttps://orcid.org/0000-0003-3734-2779МеньшиковК. В.MenshikovK. V.

Меньшиков Константин Викторович — к.м.н., доцент, кафедра онкологии с курсами онкологии и патологической анатомии ИДПО, отдел химиотерапии

Россия, Республика Башкортостан, Уфа

Konstantin V. Menshikov — Cand. Sci. (Med.), Assoc. Prof., Department of Oncology with Courses of Oncology and Pathological Anatomy for Advanced Professional Education, Chemotherapy Unit

Ufa, Russian Federation

kmenshikov80@bk.ruhttps://orcid.org/0000-0003-0996-5995СултанбаевА. В.SultanbaevA. V.

Султанбаев Александр Валерьевич — к.м.н., отделение амбулаторной химиотерапии

Россия, Республика Башкортостан, Уфа

Aleksandr V. Sultanbaev — Cand. Sci. (Med.), Outpatient Chemotherapy Unit

Ufa, Russian Federation

https://orcid.org/0000-0003-1185-977XМусинШ. И.MusinSh. I.

Мусин Шамиль Исмагилович — к.м.н., хирургическое отделение № 6

Россия, Республика Башкортостан, Уфа

Shamil I. Musin — Cand. Sci. (Med.), Surgery Unit No. 6

Ufa, Russian Federation

https://orcid.org/0000-0002-8665-8895МеньшиковаИ. А.MenshikovaI. A.

Меньшикова Ирина Асхатовна — к.м.н., кафедра биологический химии

Россия, Республика Башкортостан, Уфа

Irina A. Menshikova — Cand. Sci. (Med.), Department of Biological Chemistry,

Ufa, Russian Federation

https://orcid.org/0000-0001-8340-7962НасретдиновА. Ф.NasretdinovA. F.

Насретдинов Айнур Фанутович — отделение амбулаторной химиотерапии

Россия, Республика Башкортостан, Уфа

Ainur F. Nasretdinov — Outpatient Chemotherapy Unit

Ufa, Russian Federation

https://orcid.org/0000-0001-5926-0446СултанбаеваН. И.SultanbaevaN. I.

Султанбаева Надежда Ивановна — онкологическое отделение противоопухолевой лекарственной терапии

Россия, Республика Башкортостан, Уфа

Nadezhda I. Sultanbaeva — Anticancer Drug Therapy Unit

Ufa, Russian Federation

https://orcid.org/0000-0002-2218-8337ШайхутдиновИ. Р.ShaykhutdinovI. R.

Шайхутдинов Ильнур Рафисович — клиническая стоматологическая поликлиника

Россия, Республика Башкортостан, Уфа

Ilnur R. Shaykhutdinov — Dental Outpatient Clinic

Ufa, Russian Federation

Республиканский клинический онкологический диспансер; Башкирский государственный медицинский университетРоссияRepublican Clinical Oncological Dispensary; Bashkir State Medical UniversityRussian FederationРеспубликанский клинический онкологический диспансерРоссияRepublican Clinical Oncological DispensaryRussian FederationБашкирский государственный медицинский университетРоссияBashkir State Medical UniversityRussian Federation202122052021112174182Copyright © Меньшиков К.В., Султанбаев А.В., Мусин Ш.И., Меньшикова И.А., Насретдинов А.Ф., Султанбаева Н.И., Шайхутдинов И.Р., 20212021Меньшиков К.В., Султанбаев А.В., Мусин Ш.И., Меньшикова И.А., Насретдинов А.Ф., Султанбаева Н.И., Шайхутдинов И.Р.Menshikov K.V., Sultanbaev A.V., Musin S.I., Menshikova I.A., Nasretdinov A.F., Sultanbaeva N.I., Shaykhutdinov I.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.surgonco.ru/jour/article/view/588

Нейроэндокринные опухоли (НЭО) представляют собой гетерогенную группу злокачественных новообразований с разнообразной морфологией и номенклатурой. Исторически высокодифференцированные НЭО назывались карциноидными опухолями — термин, который привел ко многим ошибкам и путанице в классификациях. Учитывая распределение NE клеток по всему телу, были описаны случаи НЭО в центральной нервной системе, дыхательных путях, гортани, желудочно-кишечном тракте, щитовидной железе, коже, молочной железе и мочеполовой системе. Данные об эпидемиологии НЭО различны. По мнению некоторых авторов, НЭО составляют около 0,5 % всех вновь диагностированных злокачественных новообразований. Достаточно актуальным является так называемый карциноидный синдром, сопровождающий НЭО. Наличие карциноидного синдрома, возникающего в результате гиперсекреции аминов и пептидов, часто облегчает диагностику НЭО. Основным методом лечения является хирургический с лечебной целью, если это осуществимо технически. Необходимость адъювантной терапии сомнительна. В случае если операция невозможна из-за распространенности заболевания, так как большинство НЭО диагностируются на продвинутой стадии, лекарственная терапия проводится для уменьшения симптомов и контроля за заболеванием.

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The authors declare that there are no conflicts of interest present.