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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">surgonco</journal-id><journal-title-group><journal-title xml:lang="ru">Креативная хирургия и онкология</journal-title><trans-title-group xml:lang="en"><trans-title>Creative surgery and oncology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2076-3093</issn><issn pub-type="epub">2307-0501</issn><publisher><publisher-name>Башкирский государственный медицинский университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24060/2076-3093-2022-12-4-288-294</article-id><article-id custom-type="elpub" pub-id-type="custom">surgonco-733</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>Симптоматическая терапия на фоне коррекции белково-энергетической недостаточности у больных генерализованными формами рака желудочно-кишечного тракта</article-title><trans-title-group xml:lang="en"><trans-title>Supportive care against correcting protein-energy malnutrition in patients with generalized gastrointestinal cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>О. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>O. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петрова Ольга Михайловна — отделение общей онкологии, кафедра онкологии с курсами онкологии и патологической анатомии ИДПО</p><p>Уфа</p></bio><bio xml:lang="en"><p>Olga M. Petrova — General Oncology Unit, Department of Oncology with Courses of Oncology and Pathological Anatomy for Advanced ProfessionalEducation</p><p>Ufa</p></bio><email xlink:type="simple">foxy1906@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8867-504X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Липатов</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Lipatov</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Липатов Олег Николаевич — д.м.н., профессор, кафедра онкологии с курсами онкологии и патологической анатомии ИДПО</p><p>Уфа</p></bio><bio xml:lang="en"><p>Oleg N. Lipatov — Dr. Sci. (Med.), Prof., Department of Oncology with Courses of Oncology and Pathological Anatomy for Advanced Professional Education</p><p>Ufa</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудряшова</surname><given-names>Л. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudryashova</surname><given-names>L. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кудряшова Любовь Николаевна — к.м.н., отделение общей онкологии, кафедра онкологии с курсами онкологии и патологической анатомии ИДПО</p><p>Уфа</p></bio><bio xml:lang="en"><p>Lubov N. Kudryashova — Cand. Sci. (Med.), General Oncology Unit, Department of Oncology with Courses of Oncology and Pathological Anatomy for Advanced Professional Education</p><p>Ufa</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Башкирский государственный медицинский университет; Республиканский клинический онкологический диспансер</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Bashkir State Medical University; Republican Clinical Oncological Dispensary</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>02</day><month>01</month><year>2023</year></pub-date><volume>12</volume><issue>4</issue><fpage>288</fpage><lpage>294</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петрова О.М., Липатов О.Н., Кудряшова Л.Н., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Петрова О.М., Липатов О.Н., Кудряшова Л.Н.</copyright-holder><copyright-holder xml:lang="en">Petrova O.M., Lipatov O.N., Kudryashova L.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.surgonco.ru/jour/article/view/733">https://www.surgonco.ru/jour/article/view/733</self-uri><abstract><sec><title>Введение</title><p>Введение. Снижение питания у онкологических больных влияет на снижение всех жизненно важных функций организма, и, как показывают многочисленные исследования, это чаще всего пациенты с заболеваниями желудочно-кишечного тракта.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В статье отражены результаты проведенного исследования влияния коррекции белково-энергетической недостаточности на проявление основных симптомов, таких как боль, общая слабость, нарушение сна, снижение аппетита, тошнота, рвота, запоры и диарея у больных генерализованными формами рака органов желудочно-кишечного тракта. Исследование проводилось методом анкетирования до и через три месяца от начала исследования в трех равнозначных по критериям отбора группах. Для этих целей у пациентов, участвующих в исследовании, использовалось специализированное питание nutridrinc compact protein и полиненасыщенные омега-3 жирные кислоты.</p></sec><sec><title>Результаты и обсуждение</title><p>Результаты и обсуждение. В результате проведенного исследования установлено, что своевременная нутритивная поддержка положительно влияет на снижение негативных симптомов, сопровождающих онкологические заболевания, и на фоне симптоматической и противоболевой терапии дает значительно лучшие результаты в повышении качества жизни.</p></sec><sec><title>Заключение</title><p>Заключение. Своевременная нутритивная поддержка положительно влияет на снижение негативных симптомов, сопровождающих онкологические заболевания (боль, общую слабость, сон, нарушение аппетита, тошноту, рвоту, запор и диарею) и на фоне симптоматической и противоболевой терапии дает значительно лучшие результаты в повышении качества жизни.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. A decrease in nutrition of cancer patients affects all vital functions of the body, which is, according to numerous studies, typical of patients with gastrointestinal disturbances.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The study was set out to investigate the effect of correcting protein-energy malnutrition on the symptoms manifestation, including pain, fatigue, sleep disorder, poor appetite, nausea, vomiting, constipation and diarrhea in patients with generalized forms of gastrointestinal cancer. The study involved questionnaire method applied prior to the study and three months after. Three groups, equivalent in terms of selection criteria, participated in the study. For this purpose, the study participants were given nutridrink compact protein and omega-3 polyunsaturated fatty acid.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. This study found out that timely nutritional support contributes toward reducing the negative symptoms of cancer and, when combined with supportive care and pain management, leads to significantly better results in terms of improving quality of life.</p></sec><sec><title>Conclusion</title><p>Conclusion. Timely nutritional support has a positive effect on reducing the negative symptoms associated with cancer (pain, fatigue, sleep disorder, poor appetite, nausea, vomiting, constipation and diarrhea), and, along with supportive care and pain management, improves the quality of life more significantly.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>нутритивная поддержка</kwd><kwd>белково-энергетическая недостаточность</kwd><kwd>рак желудочно-кишечного тракта</kwd><kwd>нутритивный статус</kwd><kwd>боль</kwd><kwd>симптоматическая терапия</kwd><kwd>качество жизни</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nutritional support</kwd><kwd>protein-energy malnutrition</kwd><kwd>gastrointestinal cancer</kwd><kwd>nutritional status</kwd><kwd>pain</kwd><kwd>supportive care</kwd><kwd>quality of life</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн А.Д., Старинский В.В., Петрова Г.В. 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