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THE RESEARCH OF OSTEOPLASTIC PROPERTIES OF RESORBABLE POLY-3-HYDROXYBUTYRATE IN vIvO ON MODELS OF SEGMENTAL OSTEOTOMY

https://doi.org/10.24060/2076-3093-2012-0-4-48-52

Abstract

A family of materials  based  on biodegradable polymer-3-hydroxybutyric acid (polyhydroxybutyrate, PHB) has been  developed for the purposes of reparative osteogenesis. Osteoplastic properties of bulk implants  PHB and PHB composition with hydroxyapatite (HA) have been  investigated in comparison with branded drugs Bio-Oss ® in vivo via the model of segmental osteotomy. It is indicated that  reconstructive bone  formation is more  active when implants  with PHB as a main component are used.

About the Authors

E. I. Shishatskaya
Siberian Federal University; Institute of Biophysics of Russian Academy of Science
Russian Federation


Yu. S. Vinnik
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


N. M. Markelova
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


I. V. Kamendov
Krasnoyarsk Dental Research Centre on diabetes
Russian Federation


S. I. Starosvetsky
Krasnoyarsk Dental Research Centre on diabetes
Russian Federation


V. A. Khorzhevsky
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


O. V. Peryanova
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


A. А. Shumilova
Institute of Biophysics of Russian Academy of Science
Russian Federation


R. A. Pakhomova
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


E. S. Vasilenya
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


M. N. Kuznetsov
Prof. V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Russian Federation


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Review

For citations:


Shishatskaya E.I., Vinnik Yu.S., Markelova N.M., Kamendov I.V., Starosvetsky S.I., Khorzhevsky V.A., Peryanova O.V., Shumilova A.А., Pakhomova R.A., Vasilenya E.S., Kuznetsov M.N. THE RESEARCH OF OSTEOPLASTIC PROPERTIES OF RESORBABLE POLY-3-HYDROXYBUTYRATE IN vIvO ON MODELS OF SEGMENTAL OSTEOTOMY. Creative surgery and oncology. 2012;(4):48-52. (In Russ.) https://doi.org/10.24060/2076-3093-2012-0-4-48-52

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ISSN 2076-3093 (Print)
ISSN 2307-0501 (Online)