Preview

Creative surgery and oncology

Advanced search

Methods of Controlling Postoperative Complications after Lymphadenectomy in Patients with Breast Cancer

https://doi.org/10.24060/2076-3093-2024-14-3-229-234

Abstract

Introduction. Reducing the aggressiveness of surgical tactics is currently considered a promising trend in medicine that is widely supported due to its better safety profile. However, a large percentage of patients need more intervention. In the treatment of breast cancer, the main difficulties in postoperative management are associated with lymphatic surgery. Aim. To perform a comparative analysis of techniques for intraoperative control of lymphorrhea in patients during lymph node dissection for breast cancer in Yaroslavl Regional Oncologic Hospital. Materials and methods. Case histories of 660 patients after axillary subclavian subscapular lymphadenectomy were analyzed. In the postoperative period, patients revealed prolonged lymphorrhea. Magnifying techniques (binocular lenses, microscope) were used during the interventions to detect and isolate lymphatic vessels in 108 patients. A double coagulation technique was used to ligate the lymphatic vessels. Sufficient coagulation surface was achieved by forming suture lines of an angle greater than 90°. When performing a mastectomy, the technique was supplemented by circular bandaging of the chest. Results and discussion. Analysis of case histories showed that lymphadenectomy proved to be the main significant factor influencing lymphorrhea. Sparing techniques reduced the risk of postmastectomy syndrome. Comparing the study group with the control group revealed a statistically significant reduction in the severity of lymphorrhea without an increase in the risk of other complications. Conclusion. The combination of these techniques demonstrated statistically significant advantages in controlling postoperative complications. The techniques are easy to perform, therefore, they can be introduced into practice with minimal costs. The economic benefits are associated with the absence of additional costs for surgery, as well as with a reduction in the duration of hospital stay for patients. All this significantly increases patient satisfaction with the treatment performed.

About the Authors

E. M. Bukin
Regional Clinical Oncological Hospital
Russian Federation

Eduard M. Bukin — Breast and Skin Tumors Uni

Yaroslavl



A. B. Vasin
Regional Clinical Oncological Hospital
Russian Federation

Alexander B. Vasin

Yaroslavl



N. S. Goloshchapova
Regional Clinical Oncological Hospital
Russian Federation

Natalya S. Goloshchapova — Day Hospital

Yaroslavl



I. N. Roschin
Regional Clinical Oncological Hospital
Russian Federation

Igor N. Roschin — Cand. Sci. (Med.), Thoracic Oncology Unit

Yaroslavl



A. E. Akimova
Regional Clinical Oncological Hospital
Russian Federation

Anastasia E. Akimova — Breast and Skin Tumors Unit

Yaroslavl



References

1. Kaprin A.D., Starinsky V.V., Shakhzadova A.O. Malignant neoplasms in Russia in 2020 (morbidity and mortality). Moscow: National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation; 2021 (In Russ.).

2. Magnoni F., Galimberti V., Corso G., Intra M., Sacchini V., Veronesi P. Axillary surgery in breast cancer: An updated historical perspective. Semin Oncol. 2020;47(6):341–52. DOI: 10.1053/j.seminon-col.2020.09.001

3. Ganusevich O.N., Nesterovich T.N., Fedorkevich I.V. Modern approaches to breast cancer treatment (by the proceedings of St. Gallen International Breast Cancer Conference, 2017). Health and Ecology Issues. 2018;3:11–8 (In Russ.) DOI: 10.51523/2708-6011.2018-15-3-3

4. Li H., Li W.B., Sun Z.X., Yu J., Lv P.Y., Li C.X., et al. Analysis of the risk factors of breast cancer-related lymphedema and construction and evaluation of a prediction model. Lymphat Res Biol. 2023;21(6):565– 73. DOI: 10.1089/lrb.2022.0058

5. Ogiya A., Kimura K., Ueno T., Iwase T., Ohno S. Time trend of breast cancer-related lymphedema according to body mass index. Eur J Surg Oncol. 2024;50(6):108350. DOI: 10.1016/j.ejso.2024.108350

6. Chen S.Y., Tang Y., Wang S.L., Song Y.W., Fang H., Wang J.Y., et al. Timing of chemotherapy and radiotherapy following breast-conserving surgery for early-stage breast cancer: a retrospective analysis. Front Oncol. 2020;10:571390. DOI: 10.3389/fonc.2020.571390

7. Breast cancer. Clinical guidelines. Moscow, 2021 [cited 2024 June 05]. Available from: https://cr.minzdrav.gov.ru/schema/379_4.

8. Roy S., Gupta S.S., Singh U., Anand R., Bhat G., Sooraj R., et al. Prospective study to evaluate efficacy of single versus double drains in breast cancer patients undergoing surgery. Indian J Surg Oncol. 2024;15(2):437–45. DOI: 10.1007/s13193-024-01923-z

9. Marco E., Trépanier G., Chang E., Mauti E., Jones J.M., Zhong T. Postmastectomy Functional Impairments. Curr Oncol Rep. 2023;25(12):1445–53. DOI: 10.1007/s11912-023-01474-6

10. Fatuev O.E., Kozlov N.S., Korolyuk G.M., Ratke I.A., Ronzin A.V., Stepanyants N.S., et al. New approaches to prevention and treatment of early and late postoperative limphorrhea. Research and Practical Medicine Journal. 2019;6(1):60–74 (In Russ.). DOI: 10.17709/2409-2231-2019-6-1-6

11. Bogdanov A.V., Kurakina I.S., Nokhrin D.Yu. Prevention of prolonged and profuse lymphorrhea in breast cancer. P.A. Herzen Journal of Oncology = Onkologiya. Zhurnal im. P.A. Gertsena. 2020;9(3):34–40 (In Russ.). DOI: 10.17116/onkolog2020903134

12. Spiekerman van Weezelenburg M.A., Bakens M.J.A.M., Daemen J.H.T., Aldenhoven L., van Haaren E.R.M., Janssen A., et al. Prevention of seroma formation and its sequelae after axillary lymph node dissection: an up-to-date systematic review and guideline for surgeons. Ann Surg Oncol. 2024;31(3):1643–52. DOI: 10.1245/s10434-023-14631-9

13. Cherkasov M.A., Chernyi A.G., Shubnyakov I.I., Irzhanski F.A., Idrisov K.K., Dzamikhov R.K. Integrated quality assessment of medical care from patient’s standpoint. Novosti Khirurgii. 2019;27(1):49–58 (In Russ.). DOI: 10.18484/2305-0047.2019.1.49

14. Filipoiu F., Dogaru I.A., Munteanu O., Anca Monica O.M., Tulin A.D., Ursut B.M. Axillary Lymphadenectomy: Safe Dissection Through a Correct Technique. Cureus. 2024;16(1):e52434. DOI: 10.7759/cureus.52434

15. Manouras A., Markogiannakis H., Genetzakis M., Filippakis G.M., Lagoudianakis E.E., Kafiri G., et al. Modified radical mastectomy with axillary dissection using the electrothermal bipolar vessel sealing system. Arch Surg. 2008;143(6):575–80. DOI: 10.1001/archsurg.143.6.575

16. Melhem J., Amarin M., Odeh G., Al-Bustami N., Al-Lauzy H., Ayoub R. Intercostobrachial Nerve (ICBN) preservation versus sacrifice in axillary dissection: randomized controlled trial. Am J Clin Oncol. 2021;44(5):206–9. DOI: 10.1097/COC.0000000000000809

17. Bukin E.M. Method for intraoperative prevention of lymphorrhea when performing radical mastectomy or radical resection of mammary gland with axillarysubclavian-subclavian lymph node dissection: Russian Federation patent 20090135302 C1 2023 May 02.


Review

For citations:


Bukin E.M., Vasin A.B., Goloshchapova N.S., Roschin I.N., Akimova A.E. Methods of Controlling Postoperative Complications after Lymphadenectomy in Patients with Breast Cancer. Creative surgery and oncology. 2024;14(3):229-234. (In Russ.) https://doi.org/10.24060/2076-3093-2024-14-3-229-234

Views: 400


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2076-3093 (Print)
ISSN 2307-0501 (Online)