CHEMOTHERAPY INFUSION INTO THE BRONCHIAL ARTERY IN THE COMBINED TREATMENT OF THE NON-SMAL CELL LUNG CANCER OF III STAGE
https://doi.org/10.24060/2076-3093-2012-0-1-14-17
Abstract
IThe results of neoadjuvant chemotherapy of 50 patients with small cell lung cancer were analyzed. At 11 (22 %) patients at the primary reference took place atelectasis the struck share or all lung. To all patients it has been lead on two cycles neoadjuvant chemotherapy. After one rate of chemotherapy at 21 (42 %) patients note partial regress of process. After 2х rates of chemotherapy at 38 (76 %) patients note partial regress of process. From 50 patients are subjected to surgical treatment 35 (70 %) patients. From 35 operated patients in 25 cases it is made expanded pulmonectomy, and 10 cases combination expanded pulmonectomy with a resection of a pericardium with intrapericardial, separate processing of vessels of a root of a lung. Application citostatics in a mode of intraarterial introduction can improve direct results of treatment on 10-15 % that will enable effectively to finish treatment under the chosen program.
About the Authors
D. T. ArybzhanovKazakhstan
S. E. Ospanov
Kazakhstan
N. K. Ormanov
Kazakhstan
D. S. Seksenbaev
Kazakhstan
A. N. Ormanov
Kazakhstan
References
1. Абисатов Х.А. Клиническая онкология (руководство). – Алматы: изд. «Арыс», 2007. 1240 с.
2. Давыдов М.И., Полоцкий Б.Е. Рак легкого. М.: «Радикс», 1994. С. 210.
3. Кулакеев О.К., Арыбжанов Д.Т., Юсупов А.М. и др. Эффективность неоадъювантной химиотерапии немелкоклеточного рака легкого // Актуальные проблемы клинической онкологии: Республ. научнопрактич. Конференция. Семей, 2007. С. 150-151.
4. Кулакеев О.К., Арыбжанов Д.Т., Султанов Р.Р. Результаты лечения рака легкого // Вестник хирургии Казахстана. №3. – 2005. С. 113.
5. Онкология. Клинические рекомендации // Под ред. В.И.Чиссова и С.Л.Дарьяловой. – Москва: ГЭОТАР-«Медиа», 2006. С. 193-230.
6. Орлова Р.В. Современное стандартное лечение больных немелкоклеточным раком легкого с учетом стадии заболевания // Практическая онкология. – 2000. №3. – С. 17-20.
7. Переводчикова Н.И. Химиотерапия немелкоклеточного рака легкого – состояние проблемы в 2000 г. // Практическая онкология. – 2000. №3. – С. 29-37.
8. Трахтенберг А.Х., Чиссов В.И. Клиническая онко-пульмонология. –Москва: ГЭОТАР «Медицина», 2000. – 600 с.
9. Харченко В.П., Кузьмин И.В. Рак легкого. – М.: «Медицина», 1994 С. 480.
10. Burkhart N.M., Allen M.S., Nichols F.C. et. al. Results of en bloc resection for bronchogenic carcinoma with chest wall invasion // J. Thorac. Cardiovasc. Surg, 2002. Vol. 123. P. 670-675.
11. Curan W.J. Issues in the nonoperative management of patients with locally advanced non-small cell lung cancer // Proc. ASCO. 1999. P. 370-373.
12. Holmes A.C. Surgical adjuvant therapy for stage II and stage III adenocarcinoma and large cell undifferentiated carcinoma // Chest. 1994. Vol. 106. №6. P. 293-296.
13. Gumerlock P.H. Molecular-clinical correlative studies in non-small cell lung carcinoma // ASCO. - 1999. P. 374-381.
14. Kelly K. Future Directions for New Cytotoxic Agents in the treatment of аdvanced non-small-cell lung cancer // Proc. ASCO. — 2000. — Educational book. P. 357-367.
15. Marsiglia H., Baldeyrou P., Lartigau E. et.al. Highdose-rate brachyterapy as sole modality for early-stage endobronchial carcinoma // Inter. J. Radiat Oncol. Biol. Phys. – 2000. Vol. 47. P. 665-672.
Review
For citations:
Arybzhanov D.T., Ospanov S.E., Ormanov N.K., Seksenbaev D.S., Ormanov A.N. CHEMOTHERAPY INFUSION INTO THE BRONCHIAL ARTERY IN THE COMBINED TREATMENT OF THE NON-SMAL CELL LUNG CANCER OF III STAGE. Creative surgery and oncology. 2012;(1):14-17. (In Russ.) https://doi.org/10.24060/2076-3093-2012-0-1-14-17