Corporoplasty in Peyronie’s Disease: a Literature Review

Corporoplasty is urological correction surgery for penile deviation that causes copulatory dysfunction or aesthetic discomfort. Penile deviation can be congenital or acquired (Peyronie’s disease, penile fracture). Congenital penile deviation is relatively rare and manifests in the curvature of erect penis ventrally and/or laterally, in most cases. According to many studies, patients with curvatures of 30° or more eventually seek surgical treatment. Congenital curvature may be mistaken for Peyronie’s disease for similar manifestations that, however, differ in aetiology and pathophysiology. Excisional, incisional corporoplasty or plication are commonly engaged to treat congenital curvatures, in various techniques and modifications. Augmentation transplantation (grafting) and penile prosthesis implantation with variant deviation treatment options are the usual practice in Peyronie’s disease. Unequivocal judgment of pros and cons in any particular technique is nevertheless implausible to make. This article aims to review current trends, protocols and their relative advantages in corporoplasty.

1. Mayer M., Rey Valzacchi G., Silva Garretón A., Layus O., Gueglio G. Patient satisfaction with correction of congenital penile curvature. Actas Urol Esp. 2018;42(6):414–9. DOI: 10.1016/j.acuro.2017.11.002

2. Ziegelmann M.J., Bajic P., Levine L.A. Peyronie’s disease: Contemporary evaluation and management. Int J Urol. 2020;27(6):504–16. DOI: 10.1111/iju.14230

3. Sasso F., Vittori M., D’Addessi A., Bassi P.F. Penile curvature: an update for management from 20 years experience in a high volume centre. Urologia. 2016;83(3):130–8. DOI: 10.5301/uro.5000169

4. Ziegelmann M.J., Farrell M.R., Levine L.A. Clinical characteristics and surgical outcomes in men undergoing tunica albuginea plication for congenital penile curvature who present with worsening penile deformity. World J Urol. 2020;38(2):305–14. DOI: 10.1007/s00345-019-02787-7

5. Takeda M., Seo S., Sueyoshi R., Nakamura H., Suda K., Lane G.J., et al. Reconstructive surgery for recurrent penile curvature. Pediatr Surg Int. 2018;34(2):245–48. DOI: 10.1007/s00383-017-4199-8

6. Capoccia E., Levine L.A. Contemporary review of Peyronie’s disease treatment. Curr Urol Rep. 2018;19(7):51. DOI: 10.1007/s11934-018-0800-5

7. Levine L.A., Becher E.F., Bella A.J., Brant W.O., Kohler T.S., MartinezSalamanca J.I., et al. Penile prosthesis surgery: current recommendations from the international consultation on sexual medicine. J Sex Med. 2016;13(4):489–518. DOI: 10.1016/j.jsxm.2016.01.017

8. Brimley S.C., Yafi F.A., Greenberg J., Hellstrom W.J.G., Tue Nguyen H.M., Hatzichristodoulou G. Review of management options for active-phase Peyronie’s disease. Sex Med Rev. 2019;7(2):329–37. DOI: 10.1016/j.sxmr.2018.09.007

9. Kapogiannis F., Fasoulakis K., Fragkoulis C., Tsiampa E., Fasoulakis C. Reed Miller Nesbit: broadening the horizon of genitourinary surgery. Surg Innov. 2021;28(3):378–80. DOI: 10.1177/1553350620958085

10. Martenstein C., Peruth J., Hamza A. The role of Nesbit’s procedure in surgical reconstruction of penile deviation. GMS Interdiscip Plast Reconstr Surg DGPW. 2012;1:Doc06. DOI: 10.3205/iprs000006

11. Hsieh J.T., Huang H.E., Chen J., Chang H.C., Liu S.P. Modified plication of the tunica albuginea in treating congenital penile curvature. BJU Int. 2001;88(3):236–40. DOI: 10.1046/j.1464-410x.2001.02244.x

12. Kuehhas F.E., Egydio P.H. Superficial tunica albuginea excision, using geometric principles, for the correction of congenital penile curvature. BJU Int. 2012;110:E949–53. DOI: 10.1111/j.1464-410X.2012.11350.x

13. Akbulut F., Akman T., Salabas E., Dincer M., Ortac M., Kadioglu A. Neurovascular bundle dissection for Nesbit procedure in congenital penile curvature patients: medial or lateral? Asian J Androl. 2014;16:442–5. DOI: 10.4103/1008-682X.123667

14. Kuehhas F.E., Egydio P.H. The STAGE technique (superficial tunica albuginea geometric-based excision) for the correction of biplanar congenital penile curvature. J Sex Med. 2014;11:299–306. DOI: 10.1111/jsm.12346

15. Perdzyński W., Adamek M. A new corporoplasty based on stratified structure of tunica albuginea for the treatment of congenital penile curvature-long-term results. Cent European J Urol. 2015;68(1):102. DOI: 10.5173/ceju.2015.01.496

16. Perdzynski W., Adamek M. Three anatomical levels: possibilities to decrease invasiveness of reconstructive surgery for congenital penile curvature. Cent European J Urol. 2017;70(3):280–8. DOI: 10.5173/ceju.2017.1509

17. Sokolakis I., Schönbauer P., Mykoniatis I., Kübler H., Gschwend J., Lahme S., et al. Long-term results after surgical treatment of congenital penile curvature using a modified Nesbit technique. World J Mens Health. 2020;38(4):564–72. DOI: 10.5534/wjmh.190092

18. Leonardo C., De Nunzio C., Michetti P., Tartaglia N., Tubaro A., De Dominicis C., et al. Plication corporoplasty versus Nesbit operation for the correction of congenital penile curvature. A long-term follow-up. Int Urol Nephrol. 2012;44:55–60. DOI: 10.1007/s11255-011-9976-z

19. Zachalski W., Krajka K., Matuszewski M. Evaluation of the treatment of congenital penile curvature including psychosexual sassessment. J Sex Med. 2015;12:1828–35. DOI: 10.1111/jsm.12933

20. Popken G., Wetterauer U., Schultze-Seemann W., Deckart A.B., Sommerkamp H. A modified corporoplasty for treating congenital penile curvature and reducing the incidence of palpable indurations. BJU Int. 1999;83:71–5. DOI: 10.1046/j.1464-410x.1999.00887.x

21. Rolle L., Tamagnone A., Timpano M., Destefanis P., Fiori C., Ceruti C., et al. The Nesbit operation for penile curvature: an easy and effective technical modification. J Urol. 2005;173(1):171–3; discussion 173–4. DOI: 10.1097/01.ju.0000147160.53124.1a

22. Colpi G., Piediferro G., Castiglioni F., Contalbi G., Carmignani L. Penile septoplasty for congenital ventral penile curvature: results in 51 patients. J Urol. 2009;182:1489–94. DOI: 10.1016/j.juro.2009.06.059

23. Chen R., McCraw C., Lewis R. Plication procedures-excisional and incisional corporoplasty and imbrication for Peyronie’s disease. Transl Androl Urol. 2016;5(3):318–33. DOI: 10.21037/tau.2016.05.01

24. Lovasik B.P., Dodson T.F., Srinivasan J.K. Heineke, Mikulicz, Jaboulay, and Finney: innovators of surgical pyloroplasty. Am Surg. 2021;87(5):737–40. DOI: 10.1177/0003134820952820

25. Dell’Atti L., Polito M., Galosi A.B. Is degloving the best method to approach the penile corporoplasty with Yachia’s technique? Urology. 2019;126:204–8. DOI: 10.1016/j.urology.2018.12.040

26. Ghanem H., Shamloul R.M. Incisional corporoplasty for the correction of congenital penile curvature: a review of two suturing techniques. Int J Impot Res. 2008;20:222–5. DOI: 10.1038/sj.ijir.3901617

27. Sokolakis I., Hatzichristodoulou G. Current trends in the surgical treatment of congenital penile curvature. Int J Impot Res. 2020;32(1):64–74. DOI: 10.1038/s41443-019-0177-0

28. Alei G., Letizia P., Alei L., Massoni F., Ricci S. New surgical technique for ventral penile curvature without circumcision. BJU Int. 2014;113:968–74. DOI: 10.1111/bju.12539

29. Vicini P., Di Nicola S., Antonini G., De Berardinis E., Gentile V., De Marco F. Geometrical modified Nesbit corporoplasty to correct different types of penile curvature: description of the surgical procedure based on geometrical principles and long-term results. Int J Impot Res. 2016;28:209–15. DOI: 10.1038/ijir.2016.28

30. Mayer M., Rey Valzacchi G., Silva Garreton A., Layus O., Gueglio G. Patient satisfaction with correction of congenital penile curvature. Actas Urol Esp. 2017;42(6):414–9. DOI: 10.1016/j.acuro.2017.11.002

31. Hauck E.W., Bschleipfer T., Diemer T., Manning M., Schroeder-Printzen I., Weidner W. Long-term results of Essed-Schroeder plication by the use of non-absorbable Goretex sutures for correcting congenital penile curvature. Int J Impot Res. 2002;14(3):146–50. DOI: 10.1038/sj.ijir.3900827

32. Zachalski W., Matuszewski M., Krajka K., Rębała K. Familial appearance of congenital penile curvature — case history of two brothers. Cent European J Urol. 2013;66(2):217–20. DOI: 10.5173/ceju.2013.02.art27

33. Salem E.A. Modified 16-Dot plication technique for correction of penile curvature: prevention of knot-related complications. Int J Impot Res. 2018;30(3):117–21. DOI: 10.1038/s41443-018-0018-6

34. Li W.J., Bao J., Zheng D.C., Guo J., Xie M.K., Chen H.Y., et al. Treatments of Peyronie’s disease with Scutellaria baicalensis and surgery according to the disease course: a single-center retrospective study of 261 patients. Ann Palliat Med. 2021;10(3):2979–89. DOI: 10.21037/apm-20-2389

35. Deebel N.A., Scarberry K., Dutta R., Matz E., Terlecki R.P. Salvage penile plication is an effective modality for resolving residual curvature after surgery for Peyronie’s disease. Sex Med. 2020;8(4):686–90. DOI: 10.1016/j.esxm.2020.09.001

36. Çayan S., Aşcı R., Efesoy O., Kocamanoğlu F., Akbay E., Yaman Ö. Comparison of patient’s satisfaction and long-term results of 2 penile plication techniques: lessons learned from 387 patients with penile curvature. Urology. 2019;129:106–12. DOI: 10.1016/j.urology.2019.02.039

37. Basiri A., Sarhangnejad R., Ghahestani S.M., Radfar M.H. Comparing absorbable and nonabsorbable sutures in corporeal plication for treatment of congenital penile curvature. Urol J. 2011;8(4):302–6. PMID: 22090050

38. Zahran A.R., Abdeldaeim H.M., Fouda K., Elgebaly O.F. Congenital penile curvature presenting as unconsummated marriage. Repair by 16-dot plication with subjectively reported patient and partner satisfaction. Arab J Urol. 2012;10:429–33. DOI: 10.1016/j.aju.2012.09.003

39. Cantoro U., Polito M., Lacetera V., Muzzonigro G. Plication corporoplasty for congenital penile curvature: our results with longterm follow-up. Int Urol Nephrol. 2014;46:1741–6. DOI: 10.1007/s11255-014-0728-8

40. Shaeer O., Shaeer K. Shaeer’s corporal rotation III: sahortening free correction of congenital penile curvature-the noncorporotomy technique. Eur Urol. 2016;69:129–34. DOI: 10.1016/j.eururo.2015.08.004

41. Menon V., Breyer B., Copp H.L., Baskin L., Disandro M., Schlomer B.J. Do adult men with untreated ventral penile curvature have adverse outcomes? J Pediatr Urol. 2016;12(1):31.e1–7. DOI: 10.1016/j.jpurol.2015.09.009

42. Hatzichristodoulou G., Osmonov D., Kübler H., Hellstrom W.J.G., Yafi F.A. Contemporary review of grafting techniques for the surgical treatment of Peyronie’s Disease. Sex Med Rev. 2017;5(4):544–52. DOI: 10.1016/j.sxmr.2017.01.006

43. Hatzichristodoulou G. Evolution of the surgical sealing patch TachoSil ® in Peyronie’s disease reconstructive surgery: technique and contemporary literature review. World J Urol. 2020;38(2):315–21. DOI: 10.1007/s00345-019-02792-w

44. Hatzichristodoulou G. Introducing the ventral sealing technique using collagen fleece for surgical therapy of patients with ventral Peyronie’s curvature: initial experience. Int J Impot Res. 2018;30(6):306–11. DOI: 10.1038/s41443-018-0044-4

45. Neijenhuijs K.I., Holtmaat K., Aaronson N.K., Holzner B., Terwee C.B., Cuijpers P., et al. The International Index of Erectile Function (IIEF) — a systematic review of measurement properties. J Sex Med. 2019;16(7):1078–91. DOI: 10.1016/j.jsxm.2019.04.010

46. Kim K.S., Jeong H.C., Choi S.W., Choi Y.S., Cho H.J., Ha U.S., et al. Electromagnetic low-intensity extracorporeal shock wave therapy in patients with erectile dysfunction: a sham-controlled, double-blind, randomized prospective study. World J Mens Health. 2020;38(2):236–42. DOI: 10.5534/wjmh.190130

47. Kyzlasov P.S., Martov A.G., Bokov A.I., Troyakov V.M., Udalov Yu.D., Zabelin M.V. Modern look at etiology, pathogenesis, treatment of Peyronie’s disease (literature review). Ural Medical Journal. 2017;6(150):140–5 (In Russ.).

48. Furr J., Hebert K., Wisenbaugh E., Gelman J. Complications of genital enlargement surgery. J Sex Med. 2018;15(12):1811–7. DOI: 10.1016/j.jsxm.2018.10.007

49. Terrier J.E., Tal R., Nelson C.J., Mulhall J.P. Penile sensory changes after plaque incision and grafting surgery for Peyronie’s disease. J Sex Med. 2018;15(10):1491–7. DOI: 10.1016/j.jsxm.2018.07.020

50. Kotov S.V., Yusufov A.G. The first attempt of vicarious corporoplasty with buccal flap in Peyronie patients. Bashkortostan Medical Journal. 2013;8(2):304–6 (In Russ.).

51. Hatzichristodoulou G. Grafting techniques for Peyronie’s disease. Transl Androl Urol. 2016;5(3):334–41. DOI: 10.21037/tau.2016.03.16

52. Sayedahmed K., Rosenhammer B., Spachmann P.J., Burger M., Aragona M., Kaftan B.T., et al. Bicentric prospective evaluation of corporoplasty with porcine small intestinal submucosa (SIS) in patients with severe Peyronie’s disease. World J Urol. 2017;35(7):1119–24. DOI: 10.1007/s00345-016-1973-5

53. Valente P., Gomes C., Tomada N. Small intestinal submucosa grafting for Peyronie disease: outcomes and patient satisfaction. Urology. 2017;100:117–24. DOI: 10.1016/j.urology.2016.09.055

54. Hatzichristodoulou G., Fiechtner S., Pyrgidis N., Gschwend J.E., Sokolakis I., Lahme S. Suture-free sealing of tunical defect with collagen fleece after partial plaque excision in 319 consecutive patients with Peyronie’s disease: the sealing technique. J Urol. 2021 Jul 6:101097JU0000000000001933. DOI: 10.1097/JU.0000000000001933

55. Otero J.R., Gómez B.G., Polo J.M., Mateo C.P., Barreras S.G., Cruz E.G., et al. Use of a lyophilized bovine pericardium graft to repair tunical defect in patients with Peyronie’s disease: experience in a clinical setting. Asian J Androl. 2017;19(3):316–20. DOI: 10.4103/1008-682X.171572

56. Wimpissinger F., Parnham A., Gutjahr G., Maksys S., Baierlein M., Stackl W. 10 Years’ plaque incision and vein grafting for Peyronie’s disease: does time matter? J Sex Med. 2016;13(1):120–8. DOI: 10.1016/j.jsxm.2015.12.004

57. Zucchi A., Silvani M., Pastore A.L., Fioretti F., Fabiani A., Villirillo T., et al. Corporoplasty using buccal mucosa graft in Peyronie disease: is it a first choice? Urology. 2015;85(3):679–83. DOI: 10.1016/j.urology.2014.10.026