Endovascular therapy in the combination treatment of widespread purulent peritonitis

Introduction. The article describes the first experience of concomitantly using regional endovascular drug administration and vacuum-assisted laparotomy in the combination therapy of widespread purulent peritonitis.

Materials and methods. In 2023 (from January to November 2023), 25 patients with widespread purulent peritonitis were treated at Surgery Unit No. 2 (Septic Surgery Unit) of the G.G. Kuvatov Republican Clinical Hospital.

 Results. The proposed treatment method was applied in three patients. The case fatality rate in the comparator group (n = 22) was 40.9 %. No fatalities were reported among patients who underwent the proposed procedure (n = 3).

Discussion. The clinical picture and dynamics of changes in proinflammatory markers (procalcitonin, blood leukocytes, and C-reactive protein) in the context of endovascular therapy indicate peritoneal inflammation relief and a possible correlation between these events.

Conclusion. We believe that the proposed treatment regimen has a positive effect in the treatment of widespread abdominal inflammatory processes and requires further study.

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