Treatment Outcomes in Patients with Biliary Ileus
https://doi.org/10.24060/2076-3093-2026-16-2-148-154
Abstract
Introduction. Although uncommon, biliary ileus is a severe complication of gallstone disease, occurring primarily in elderly patients and associated with high mortality. Aim. This study examined the clinical presentation, diagnostic features, and surgical management of biliary ileus and evaluated the effectiveness of different treatment strategies based on 15 years of clinical experience.
Materials and methods. A retrospective analysis was performed on 37 patients (32 women, 5 men; mean age 71.4 ± 9.6 years) treated in the surgical departments of three clinics in the Central region of Russia between 2010 and 2024. A cholecystoduodenal fistula was identified in 75.6% of cases, and the ileum was the most common site of gallstone impaction (62.1%).
Results. A strong association was observed between the stage of intestinal obstruction, the severity of hemodynamic disturbances, and the degree of endogenous intoxication. Mortality ranged from 7.5–10% in compensated obstruction, 15–20% in subcompensation, and 30–35% in decompensation. The primary surgical approach was isolated enterolithotomy (81.1%), which demonstrated the lowest complication rates (6.6%) and mortality (6.6%). In contrast, mortality after bowel resection reached 50%. Discussion. Radical procedures involving cholecystectomy and fistula repair are indicated only in patients with stable hemodynamics and acceptable somatic status. The degree of endogenous intoxication correlates with the severity of intestinal obstruction. These findings confirm that early diagnosis, careful hemodynamic assessment, and evaluation of endogenous intoxication are critical for selecting an appropriate treatment strategy.
Conclusion. An individualized approach and prioritization of organ‑preserving procedures reduce complication rates, shorten hospitalization, and improve prognosis in patients with biliary ileus.
Keywords
About the Authors
V. V. RybachkovRussian Federation
Vladimir V. Rybachkov — Dr. Sci. (Med.), Prof., Department of Hospital Surgery
Yaroslavl
D. E. Dubrovina
Russian Federation
Dina E. Dubrovina — Cand. Sci. (Med.), Assoc. Prof., Department of Hospital Surgery
Yaroslavl
A. V. Tevyashov
Russian Federation
Aleksandr V. Tevyashov — Cand. Sci. (Med.), Assoc. Prof., Department of Hospital Surgery
Yaroslavl
E. I. Avakian
Russian Federation
Evgeniya I. Avakian — Cand. Sci. (Med.), Department of Hospital Surgery
Yaroslavl
A. A. Kirilyuk
Russian Federation
Alexander A. Kirilyuk — Cand. Sci. (Med.), Surgery Unit No. 1
Vologda
N. M. Sadizhov
Russian Federation
Nasrulla M. Sadizhov — Cand. Sci. (Med.), Surgery Unit No. 2
Kostroma
References
1. Podoluzhny V.I., Pelts V.A., Radionov I.A., Pavlenko V.V., Startsev A.B. Vesico-duodenal fistulas and obstructive small-bowel obstruction in cholelithiasis. Medicine in Kuzbass. 2021;20(2):44–6 (In Russ.). DOI: 10.24411/2687-0053-2021-10020
2. Odishelashvili G.D., Pakhnov D.V., Odishelashvili N.G. Acute gallstone intestinal obstruction. Caspian Journal of Medicine and Pharmacy. 2022;3(1):59–63 (In Russ.). DOI: 10.48612/agmu/2022.3.1.59.63
3. Inukai K. Gallstone ileus: a review. BMJ Open Gastroenterol. 2019;6(1):e000344. DOI: 10.1136/bmjgast-2019-000344
4. Liu Y.Y., Bi S.Y., He Q.R., Fan Y., Wu S.D. Developments in the diagnosis and management of cholecystoenteric fistula. J Invest Surg. 2022;35(11-12):1841–6. DOI: 10.1080/08941939.2022.2113188
5. Ryabkov I.A., Tomnuyk N.D., Danilina E.P. Acute intestinal obstruction as a complication of cholelitiasis. International Journal of Applied and Fundamental Research. 2016;(8-3):402–3 (In Russ.).
6. Alnagar A., Elkomy H., Foula M., Sakr M., Nabil W. Laparoscopic management of cholecysto-duodenal fistula after spontaneous resolution of intestinal obstruction component of gallstone ileus case report and literature review. Rozhl Chir. 2022;101(1):42–5. DOI: 10.33699/PIS.2022.101.1.42-45
7. Boudou M., Jabi R., Maamar K., Soussan H., Taibi S., Bouziane M. A febrile occlusion revealing a biliary ileus. Int J Surg Case Rep. 2022;94:107113. DOI: 10.1016/j.ijscr.2022.107113
8. Shishkina G.A., Petryashev A.V., Topuzov R.E., Balashov V.K., Khalukhoeva Z.A., Runova A.V., et al. Cholelithiasis intestinal obstruction. HERALD of North-Western State Medical University named after I.I. Mechnikov. 2025;17(1):106–12 (In Russ.). DOI: 10.17816/mechnikov633307
9. Subbotin V.M., Busyrev Yu.B., Davidov M.I., Nikonova O.E. Biliary ileus. Herald of Surgical Gastroenterology. 2015;(3–4):19–22 (In Russ.).
10. Vinnik Yu.S., Teplyakova O.V., Volkov Yu.M., Bulaev A.A., Ponedelnik D.N. Gallstone ileus in a middle-aged male with an atypical history: A case report. Acta Biomedica Scientifica. 2022;7(2):261–71 (In Russ.). DOI: 10.29413/ABS.2022-7.2.26
11. Alemi F., Seiser N., Ayloo S. Gallstone disease: cholecystitis, Mirizzi syndrome, Bouveret syndrome, gallstone ileus. Surg Clin North Am. 2019;99(2):231–44. DOI: 10.1016/j.suc.2018.12.006
12. Beburishvili A.G., Panin S.I., Puzikova A.V. Diagnostics and treatment of Bouveret syndrome (literature review). Bulletin of Volgograd State Medical University. 2019;3(71):9–13 (In Russ.). DOI: 10.19163/1994-9480-2019-3(71)-9-13
13. Alzerwi N.A.N., Idrees B., Alsareii S., Aldebasi Y., Alsultan A. The regularity of the site of impaction in recurrent gallstone ileus: a systematic review and meta-analysis of reported cases. Can J Gastroenterol Hepatol. 2021;2021:5539789. DOI: 10.1155/2021/5539789
14. Toh J.W., Balasuriya H., Stewart P. An unusual cause of large-bowel obstruction: cholecystocolonic fistula and gallstone ileus. Clin Gastroenterol Hepatol. 2016;14(9):e107-8. DOI: 10.1016/j.cgh.2016.03.028
15. Vera-Mansilla C., Sanchez-Gollarte A., Matias B., Mendoza-Moreno F., Díez-Alonso M., Garcia-Moreno Nisa F. Surgical treatment of gallstone ileus: less is more. Visc Med. 2022;38(1):72–7. DOI: 10.1159/000518451
16. Muthukumarasamy G., Venkata S.P., Shaikh I.A., Somani B.K., Ravindran R. Gallstone ileus: surgical strategies and clinical outcome. J Dig Dis. 2008;9(3):156–61. DOI: 10.1111/j.1751-2980.2008.00338.x
17. Ploneda-Valencia C.F., Gallo-Morales M., Rinchon C., Navarro-Muñiz E., Bautista-López C.A., de la Cerda-Trujillo L.F., et al. Gallstone ileus: An overview of the literature. Rev Gastroenterol Mex. 2017;82(3):248–54. DOI: 10.1016/j.rgmx.2016.07.006
18. Augustin G., Bruketa T., Kunjko K., Romić I., Mikuš M., Vrbanić A., et al. Colonic gallstone ileus: a systematic literature review with a diagnostic-therapeutic algorithm. Updates Surg. 2023;75(5):1071–82. DOI: 10.1007/s13304-023-01537-0
19. Beuran M., Ivanov I., Venter M. Gallstone ileus — clinical and therapeutic aspects. J Med Life. 2010;3(4):365–71. PMC3019077.
20. Vadher D., Zacken A., Shah V., Silmi M., Aguilar L.S., Patel K., et al. The Rolling stones: a systematic review and meta-analysis of the management of gallstone ileus. Chirurgia (Bucur). 2024;119(5):483–514. DOI: 10.21614/chirurgia.3046
21. Kochukhov V.P., Vasilenko O., Platonov A.Yu., Bunin V.I., Popova I.E., Onishchenko M.P. Biliary ileus. Surgical Practice). 2017;2:53– 6 (In Russ.).
22. Khadjibaev F.A., Alidjanov F.B., Kurbonov A.B. Clinical and instrumental diagnostics of gallstone ileus. Am J Medicine Med Sci. 2020;10(9):697–701. DOI: 10.5923/j.ajmms.20201009.14
23. Gaikwad S., Marathe M. Gallstone ileus: clinical presentation and radiological diagnosis. Cureus. 2023;15(7):e42059. DOI: 10.7759/cureus.42059
24. Kumar H.R. Overview on gallstone ileus: update on management. Asian J Med Health. 2024;22(12):224–31. DOI: 10.9734/ajmah/2024/v22i12792
25. Nuño-Guzmán C.M., Marín-Contreras M.E., Figueroa-Sánchez M., Corona J.L., Salvador-Sánchez F., Méndez-Zermeño C. Gallstone ileus, clinical presentation, diagnostic and treatment approach. World J Gastrointest Surg. 2016;8(1):65–76. DOI: 10.4240/wjgs.v8.i1.65
26. Reisner R.M., Cohen J.R. Gallstone ileus: review of 1001 cases. Am Surg. 1994;60(6):441–6. PMID: 8198337.
27. Arablinskii A.V., Buslavskaya A., Titov M.YU. The Role of computed tomography in the diagnosis of biliary ileus as a cause of “acute abdomen”. Diagnostic and Interventional Radiology. 2024;18(1):40–50 (In Russ.).
28. Korovin A.Ya., Trifanov N.A., Bazlov S.B., Turkin D.V. Biliary ileus. Modern Problems of Science and Education. 2019;2 (In Russ.). DOI: 10.17513/spno.28737
29. Jakubauskas M., Luksaite R., Sileikis A., Strupas K., Poskus T. Gallstone ileus: management and clinical outcomes. Medicina (Kaunas). 2019;55(9):598. DOI: 10.3390/medicina55090598
30. Gupta V., Abhinav A., Vuthaluru S., Kalra S., Bhalla A., Rao A.K., et al. The multifaceted impact of gallstones: understanding complications and management strategies. Cureus. 2024;16(6):e62500. DOI: 10.7759/cureus.62500
31. Mamchich V.I., Bondarenko N.D., Chaika M.A. New in the problem gallstone bowel obstruction. Annals of Surgical Hepatology. 2020;25(1):62–8 (In Russ.). DOI: 10.16931/1995-5464.2020162-68
Review
For citations:
Rybachkov V.V., Dubrovina D.E., Tevyashov A.V., Avakian E.I., Kirilyuk A.A., Sadizhov N.M. Treatment Outcomes in Patients with Biliary Ileus. Creative surgery and oncology. 2026;16(2):148-154. (In Russ.) https://doi.org/10.24060/2076-3093-2026-16-2-148-154
JATS XML


























