RESULTS OF TRANSARTERIAL CHEMOEMBOLIZATION OF STOMACH CANCER METASTASES IN THE LIVER

Abstract

Results of treatment of 60 patients with gastric  cancer  with liver metastases are analyzed. Immediate results have shown  the effectiveness of treatment after 2 cycles of TACE in 49(81,7%) patients: partial response was observed in 36 (60%) patients and a significant regression of the process  was observed in 13 (21,6%) patients, the process  of stabilization was observed in 11 (18,3%) patients. Subsequent evaluation of the effectiveness of the results of treatment of patients after 4 and 6 courses of TACE were identical. Partial response was observed in the  process  of 18 (30%) patients, stabilization persisted in 12 (20%) patients.  The progression by 8-9  months of  treatment was  seen  in 30  (50%) patients. In assessing the  general  condition of patients focused on the  quality of life for patients. All patients  had  a  positive  treatment  outcome  overall  by  Karnovsky  remained  at  the  level  of 75-80% (ECOG 1-2), which does not limit the patients and did not require prolonged hospitalization. The average time of hospitalization of patients with each course  (cycle) TACE averaged 5±2  day. In the dynamic tracking  of patients in terms  of 12, 18, 24 months more than 12 months 24 (40%) patients are alive, 11 (18,3%) patients are alive during 18 months.  8 (13,3%) patients are alive during 24 months. Median survival was 15,5±1,2 months.

Thus, in the present the TACE method in stomach cancer metastasis treatment can be considered like an effective, low toxicity method of  treatment and  may be a method of choice for improving survival and quality of life of the difficult category of patients.