The research of surgical material including a primary breast tumor, lymphatic basins with lymph nodes revealed the fact of neo-lymphatic genesis of breast cancer patients. Evidentiary basis  of the genetic  lymphoid  re-forming  is  made   with  the use  of modern biological technologies. Inflammatory chemokines’ expression profile and  their receptors in newly formed lymph nodes  during breast cancer  were analyzed. The analysis revealed an increase in CCL16, XCR1, CYFIP2, TNFSF14 genes  and  a decrease in CXCL5 and  CXCL12 chemokines’ ligands in newly formed lymph nodes .The data got are of a great scientific importance.

The purpose of this study  was to evaluate the  tolerability  and effects on the  immune status of  patients with  radically resection of  non-small cell lung  cancer  new  method of intraoperative chemoimmunotherapy. Pilot results  treatment of  twenty patients indicate a satisfactory tolerability  and  positive impact  on the  immune  status. Further  study  of the effectiveness of this method as a component of the complex treatment of early-stage nonsmall cell lung cancer seems  to be promising.

IThe results  of neoadjuvant chemotherapy of 50 patients with small cell lung cancer were  analyzed. At  11  (22  %)  patients at  the  primary  reference took  place  atelectasis the  struck  share  or all lung.  To all patients it has  been  lead  on  two  cycles neoadjuvant chemotherapy. After one rate  of chemotherapy at 21 (42 %)  patients note  partial regress of process. After  2х rates  of chemotherapy at 38 (76 %)  patients note  partial  regress  of process. From 50 patients are subjected to surgical treatment 35 (70 %) patients. From 35 operated patients in 25 cases it is made expanded pulmonectomy, and 10 cases combination expanded pulmonectomy with a resection of a pericardium with intrapericardial, separate processing of vessels of a root  of a lung. Application  citostatics in a mode  of intraarterial introduction can improve direct results of treatment on 10-15 % that  will enable effectively to finish treatment under  the chosen  program.

The disease and prevalence analysis of chronic lymphatic leukemia from 1990 for 2009 was  carried  out.  Considerable growth of  prevalence CLL  both  among men  and  among women is established. Disease  and  prevalenceCLL was  statistically  signifi-cantly above among city dwellers,  than  rural. The analysis of disease  and  prevalence CLL on a sex has revealed  higher  values among men,  than  among women. At the  analysis  of  CLL on age revealed  that  the  greatest indicator  is registered in a group  of   age  80-84 years (8,05 on 100 thousand population), the least – 25-29 years (0).  Growth of disease was at the age of 45-74  and 85 years and more  elder also was re-vealed and decrease of disease  at the age of 75-84 years.

The  application of  prebiotic   Bactisporin  and  immunomodulator Immureg   was  the subject  of the research. Immureg  and Bactisporin  were applied  as additional pathogenetic medications to  treat patients suffering from  active  tuberculosis and  secondary  syphilis. The use  of  the  medications aids to  increase  the  amount of  active  phagocytes in blood. Phagocytosis intensity  and  antimicrobial potential rise. The medications also stimulate TLymphocytic  component of  immune  system  and  regulate circulating  immune  complexes and IgM Immunoglobulin in blood.

The  use  of  HIFU for  prostate cancer   treatment causes   a  significant number  of complications in the  form  of urinary incontinence, which responds poorly to conservative therapy and  reduces the  quality of life. Our results  suggest the  need  rigorous  evaluation of  the  indications for  this method of  treatment, careful  patient selection  excluding  the evidence of obstruction, and the search for effective treatments for urinary incontinence.

The study identified a set of independent prognostic risk factors for urinary incontinence, which formed the basis of a mathematical model and computer program for estimating the risk of urinary incontinence after HIFU therapy. This program can be used to determine the likelihood of disease in clinical practice, and these data are the basis of a set of measures for the prevention of urinary incontinence after HIFU therapy.

Assessment of changes in local blood flow and motor activity of the jejunum in the early postoperative period  in patients with diffuse peritonitis helps to identify  intraabdominale complications and to clarify the indications for relaparotomy.

The article analyzes  the  results  of surgical treatment of patients with traumatic brain injury using the  modified crown  cutters and  plastic round  after cranial defects. The study aims to improve the results of surgical treatment of patients with TBI. Analyzed the results of surgical treatment of 211 persons, constituting the  main group  (105 operated with the use of modified crown cutters) and control (106, operated by the classical method).Analysis of results showed a decrease in the duration of the first (bone) phase  of craniotomy and a half times in the application of the modified crown cutters.

The authors have proposed and implemented in the clinic a new method for preventing bankruptcy enteroenteroanastomosis  seams.   Surgeries  performed by  this  method, can significantly  reduce the development of insolvency seams  mezhkishechny anastomosis.

The article covers the  data  of skin melanoma advancing and  of its prevalence rate  in the Republic of Bashkortostan. Clinical cases of skin melanoma advancing among residents of the Republic of Bashkortostan are described. Treatment options of the disease  are also mentioned. Causes of high skin melanoma advancing in the  Republic of Bashkortostan  in comparison with the subjects  of  Volga Federal district are considered in the article.

The article presents an analysis of age-related characteristics of breast cancer  in the Ulyanovsk region. It says that  there  are more patients with age over 60 years has advanced stage of disease called “old” breast cancer patients and significantly  lower survival rate.

The purpose of  the  present research to raise efficiency of  treatment and  preventive maintenance of  relapses  of  patients with  urolithic  illness after a  remote lithotripsy  by application of the developed rehabilitation complexes  on the basis of phytomeans.

Work  is based  on  application of  own  patent with  use  of  phytomeans (the  Way of preventive  maintenance and complex treatment urolithic illness after a remote lithotripsy, the positive decision on delivery of the patent for the invention from 27.05.11г.) . Research is based on the clinical material including experience of treatment of 127 patients with urolithic illness from  2009  for 2010 the basic group  of 66 patients (with  application of an offered technique of complex treatment) and control group of 61 patients Has been generated. The analysis of results of treatment has shown  that  application of phytogathering for patients with urolithic illness after a remote lithotripsy promotes a conclusion  of stones, there  is an early knocking  over of inflammatory changes, phytogathering doesn’t  break  a functional condition of kidneys.  At the  same  time under  the  influence of phytogathering there  was statistically authentic increase  in volume of urine, decrease in level of nitrogenous slags (a Creatinine, urea), the tendency to decrease in the raised concentration of uric acid in whey of blood and the maintenance in urine of oxalates and uric acid Besides, isn’ted.

In surgical practice, with operations in the  duodenum using different types  of suture material. The experiment used 4 types of suture  material: Vikryl, polidiaksonon, kapron and silk. Vikryl seams can be seen as more preferable in terms of prevention cicatrices expressed changes in the intervention of intestinal  wall, while maintaining good strength properties.

The article presents a clinical experience of 58 patients with alveolar liver disease. Hepatic resection was performed in the main group  with the use of carbon  dioxide (CO2) surgical laser, purulent necrotic cavities were  treated by means of laser necrectomy and  antimicrobial photodynamic therapy with subsequent antibiotics laser activation. As the treatment outcome, radical liver resection was carried out in 39 (67,2%) patients. Hence,  in the main group  laboratory indicators normalization period was shortened from13±4,9 to 8±3,4 days (р=0,03), duration of hospital stay decreased from 32±5,8 to 25±4,8 days (р=0,02), postoperative complications incidence rate was reduced from 30,3% до 12% (р=0,05).

The paper  presents materials  of investigations directed to improvement of results  of ventral  herniotomy. Traditional  hernial  gate  plasty  supplemented with  abdominoplasty is needed and  grounded. This combination allows to  decrease significantly  the  number of nearest and remote complications and to reach better esthetic operative results. The opportunity of using apparatus HAEMO-MENTICS PCS-2 for perfection of treatment was studied. The suggested technique permits to reduce the number of nearest postoperative complications by 2,5 times and to receive good cosmetic  result in 84% of patients.

Materials   of   investigations  directed  to   reduction  of   hemorrhage  in  abdominal liposuction  are  presented in the  paper. The technique of  preventive  devascularization of abdominal wall was  grounded. The opportunity of  performing video-assisted abdominal vascular dissection as the  preliminary  stage of liposuction  was  studied. The technique of surgical operation was worked  out. Efficiency of  abdominal vascular  dissection aimed at reduction of hemorrhage was investigated The technique suggested permits to obtain more than  twofold reduction of hemorrhage in abdominal liposuction.

Breast  cancer  became one  of  the  most  important healt  care  problems in Ulyanovsk region.  Following article is written in the  context of epidemiological aspects taking  in the view morbidity, mortality  and  survival rate  of patients according their residence whether city or rural districts.

Results of an estimation of detectability of risk factors chronic noninfectious diseases among surveyed  in the health  center  are presented, the database structure on a floor and age is specified. Prevalence among different age groups is analysed. Dependence of volume of  a fatty fabric  on cholesterol level in blood  is studied. The comparative analysis of  the received results has shown  that  for timely preventive  maintenance of oncological  diseases it is necessary to reveal its signs at its early stages for what  it is successfully  possible to use anthopometry methods, bioimpedance and  ultrasonic  researches (ultrasonic). Results of ultrasonic are comparable to clinical values of anthopometrical indicators and a bioimpedance estimation of volume of a fatty fabric.indicators and a bioimpedance estimation of volume of a fatty fabric.

Evaluated the results of examination and treatment of 37 patients who were hospitalized for  surgical  in Belarus for  the  period  2000  to 2010. The experience of  dynamic  remedial laparoscopy under  local postoperative peritonitis with the use of lysozyme and polyvalent piobakteriofaga shows  the  effectiveness of this method can reduce  mortality  and  reduce treatment time by an average of 3 ± 1,3 day in chronic inflammatory diseases  caused  by associations of St. Aureus with Pr. vulgaris, Morganella morganii and Enterobacter aggl.

Direct results  nonadjuvant intraarterial chemotherapy are analysed at breast cancer  3 stages at  30 patients under  scheme  Taxotere  75mg/m2, Doxorubicini  60mg/m2. At the analysis  of  results  after 2 rates  intraarterial chemotherapy partial  regress  at  19 (63,3%) patients, stabilization of process at 11 (36,7%) patients is noted. After 4х rates intraarterial chemotherapy significant regress  of a tumor  is noted at 15 (50%) patients, partial regress at 12 (40%) patients and  stabilization of process  at 3 (10%)  patients. Thus after 4 rates nonadjuvant intraarterial chemotherapy 27 (90%) patients it is lead radical mastectomy.

The  experimental investigation that   was  carried  out  on  80  white  rats  shows  that through long term after splenectomy there  occurs proliferation of immunecompetent cells in lymphoid tissues of intestines, herewith lymphoid nodules  achieve considerable size and they  show  increased functional activity as a result  of  reproduction centers appearance. Through  long-term after organ  saving and organ  replacement operations participation of intestinal  lymphoid tissue in compensatory process  was determined. The last remained not only functionally active but with the increase of proliferate activity.

In work ways of a stop of a bleeding  are estimated at damages of a liver, a spleen. The way sewing  parenchymatous bodies  is developed. The offered seam  is applied  in clinical practice. In all supervision it was possible to provide a reliable hemostasis that  has allowed to improve considerably results of operations on parenchymatous bodies.

Patients with gastric  ulcer, associated with Helicobacter pylori infection, have passed dental  examination and  gingivitis  and  periodontal treatment with  usage  of  lyophilized kumyss lactic acid bacillus and bismuth preparation. Measure time course  of dental  health (OHI-S, PMA, PDI). Diagnostic  examination methods – urease test, microbiological, serological,  molecular  genetic  examination methods before and after treatment. Complex treatment of gastric ulcer and inflammatory periodontal diseases locally in the oral cavity by kumysand bismuth-containing preparations.

The article presents the preventive maintenance possibilities infectious complications of a postoperative wound  after radical bladder  removal with one-stage plasticity of a bladder from ilium guts at sick of a cancer of a bladder  the SPSA-VACCINE are resulted.

The review of the literature was devoted to the surgical treatment of the non-parasitic hepatic cysts. At present, significantly increased incidence of this disease, have opened new opportunities for  differential diagnosis and  choice of  treatment. An analysis of  research on  the  use  of  open  operations, and  the  results  of  laparoscopic and  minimally-invasive techniques.

Having made a literature review, the writers of the article analyze the data of native and foreign researchers on the study of neurofibromatosis type 1. They also provide the main features of pathogenesis, clinical and genetic basis of the disease, and integrate recent data on diagnosis and treatment of this disease.

Full-scaled single-stage interventions are problematic in critical conditions associated with widespread peritonitis and severe injuries of abdominal cavity organs. In such situations the mentioned volume can exceed physiological capabilities. The article deals with the survey of literature containing the analysis of leading pathophysiological syndromes during critical conditions. Special attention is given to digestive  and  abdominal hypertension. The article gives recent  literature data  about multi-stage surgery indications and techniques.